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BMC Biotechnology

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  1. Content type: Research article

    Dissolved oxygen tension (DOT) is hardly constant and homogenously distributed in a bioreactor, which can have a negative impact in the metabolism and product synthesis. However, the effects of DOT on plasmid ...

    Authors: Karim E. Jaén, Juan-Carlos Sigala, Roberto Olivares-Hernández, Karsten Niehaus and Alvaro R. Lara

    Citation: BMC Biotechnology 2017 17:60

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  2. Content type: Research article

    The environmental gliding bacteria Lysobacter are emerging as a new group of biocontrol agents due to their prolific production of lytic enzymes and potent antibiotic natural products. These bacteria are intrinsi...

    Authors: Wei Zhang, Justin Huffman, Shengying Li, Yuemao Shen and Liangcheng Du

    Citation: BMC Biotechnology 2017 17:59

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  3. Content type: Research article

    Fas ligand plays a key role in the human immune system as a major cell death inducing protein. The extracellular domain of human Fas ligand (hFasLECD) triggers apoptosis of malignant cells, and therefore is ex...

    Authors: Michiro Muraki and Kiyonori Hirota

    Citation: BMC Biotechnology 2017 17:56

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  4. Content type: Research article

    Effective and simple methods that lead to higher enzymatic efficiencies are highly sough. Here we proposed a foldon-triggered trimerization of the target enzymes with significantly improved catalytic performan...

    Authors: Xinzhe Wang, Huihua Ge, Dandan Zhang, Shuyu Wu and Guangya Zhang

    Citation: BMC Biotechnology 2017 17:57

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  5. Content type: Research Article

    Xylanase degrades xylan into monomers of various sizes by catalyzing the endohydrolysis of the 1,4-β-D-xylosidic linkage randomly, possessing potential in wide industrial applications. Most of xylanases are su...

    Authors: Tingting Shang, Dayong Si, Dongyan Zhang, Xuhui Liu, Longmei Zhao, Cong Hu, Yu Fu and Rijun Zhang

    Citation: BMC Biotechnology 2017 17:55

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  6. Content type: Methodology article

    Three-dimensional (3D) spheroids are frequently used in toxicological study because their morphology and function closely resemble those of tissue. As these properties are maintained over a long term, repeated...

    Authors: Mayu Yasunaga, Yasuko Fujita, Rumiko Saito, Mitsuo Oshimura and Yoshihiro Nakajima

    Citation: BMC Biotechnology 2017 17:54

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  7. Content type: Research article

    Alpha amylase hydrolyzes α-bonds of polysaccharides such as starch and produces malto-oligosaccharides. Its starch saccharification applications make it an essential enzyme in the textile, food and brewing ind...

    Authors: Hong Zhu, L. Bruce Reynolds and Rima Menassa

    Citation: BMC Biotechnology 2017 17:53

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  8. Content type: Research article

    Cotton fiber, a natural fiber widely used in the textile industry, is differentiated from single cell of ovule epidermis. A large number of genes are believed to be involved in fiber formation, but so far only...

    Authors: Yan-Jun Li, Shou-Hong Zhu, Xin-Yu Zhang, Yong-Chang Liu, Fei Xue, Lan-Jie Zhao and Jie Sun

    Citation: BMC Biotechnology 2017 17:50

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  9. Content type: Research article

    The discharge of poorly treated effluents into the environment has far reaching, consequential impacts on human and aquatic life forms. Thus, we evaluated the flocculating efficiency of our test bioflocculant ...

    Authors: Mayowa Oladele Agunbiade, Esta Van Heerden, Carolina H. Pohl and Anofi Tom Ashafa

    Citation: BMC Biotechnology 2017 17:51

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  10. Content type: Research article

    The Gaussia princeps luciferase is used as a stand-alone reporter of transgene expression for in vitro and in vivo expression systems due to the rapid and easy monitoring of luciferase activity. We sought to simu...

    Authors: Michael Puckette, Thomas Burrage, John G. Neilan and Max Rasmussen

    Citation: BMC Biotechnology 2017 17:52

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  11. Content type: Research article

    Somatic cell selection in plants allows the recovery of spontaneous mutants from cell cultures. When coupled with the regeneration of plants it allows an effective approach for the recovery of novel traits in ...

    Authors: Philippa J. Barrell, Julie M. Latimer, Samantha J. Baldwin, Michelle L. Thompson, Jeanne M.E. Jacobs and Anthony J. Conner

    Citation: BMC Biotechnology 2017 17:49

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  12. Content type: Research article

    Whey permeate is a lactose-rich effluent remaining after protein extraction from milk-resulting cheese whey, an abundant dairy waste. The lactose to ethanol fermentation can complete whey valorization chain by...

    Authors: Lorenzo Pasotti, Susanna Zucca, Michela Casanova, Giuseppina Micoli, Maria Gabriella Cusella De Angelis and Paolo Magni

    Citation: BMC Biotechnology 2017 17:48

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  13. Content type: Research article

    Endo-xylanases are essential in degrading hemicellulose of various lignocellulosic substrates. Hemicellulose degradation by Geobacillus spp. is facilitated by the hemicellulose utilization (HUS) locus that is pre...

    Authors: Martinus J.A. Daas, Patricia Murciano Martínez, Antonius H.P. van de Weijer, John van der Oost, Willem M. de Vos, Mirjam A. Kabel and Richard van Kranenburg

    Citation: BMC Biotechnology 2017 17:44

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  14. Content type: Methodology article

    Targeted delivery of gene therapy vectors to the mouse respiratory tract is often performed via intranasal or intratracheal administration; however, there can be a great deal of variability between these metho...

    Authors: Lisa A. Santry, Joelle C. Ingrao, Darrick L. Yu, Jondavid G. de Jong, Laura P. van Lieshout, Geoffrey A. Wood and Sarah K. Wootton

    Citation: BMC Biotechnology 2017 17:43

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  15. Content type: Research article

    Polysialic acid (polySia) is a carbohydrate modification of the neural cell adhesion molecule (NCAM), which is implicated in neural differentiation and plays an important role in tumor development and metastas...

    Authors: Stefan Somplatzki, Martina Mühlenhoff, Andrea Kröger, Rita Gerardy-Schahn and Thomas Böldicke

    Citation: BMC Biotechnology 2017 17:42

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  16. Content type: Research Article

    At first glance, there appears to be a high degree of similarity between the metabolism of yeast (the Crabtree effect) and human cancer cells (the Warburg effect). At the root of both effects is accelerated me...

    Authors: Darjan Andrejc, Alenka Možir and Matic Legiša

    Citation: BMC Biotechnology 2017 17:41

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  17. Content type: Research article

    Switchgrass is C4 perennial grass species that is being developed as a cellulosic bioenergy feedstock. It is wind-pollinated and considered to be an obligate outcrosser. Genetic engineering has been used to alter...

    Authors: Reginald Millwood, Madhugiri Nageswara-Rao, Rongjian Ye, Ellie Terry-Emert, Chelsea R. Johnson, Micaha Hanson, Jason N. Burris, Charles Kwit and C. Neal Stewart Jr

    Citation: BMC Biotechnology 2017 17:40

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  18. Content type: Research article

    Propionate is widely used as an important preservative and important chemical intermediate for synthesis of cellulose fibers, herbicides, perfumes and pharmaceuticals. Biosynthetic propionate has mainly been p...

    Authors: Jing Li, Xinna Zhu, Jing Chen, Dongdong Zhao, Xueli Zhang and Changhao Bi

    Citation: BMC Biotechnology 2017 17:38

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  19. Content type: Research article

    N-Butanol has favorable characteristics for use as either an alternative fuel or platform chemical. Bio-based n-butanol production using microbes is an emerging technology that requires further development. Al...

    Authors: Wei-Chih Chin, Kuo-Hsing Lin, Chun-Chi Liu, Kenji Tsuge and Chieh-Chen Huang

    Citation: BMC Biotechnology 2017 17:36

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  20. Content type: Research article

    Enzymatic degradation of chitin has attracted substantial attention because chitin is an abundant renewable natural resource, second only to lignocellulose, and because of the promising applications of N-acety...

    Authors: Junpei Zhou, Zhifeng Song, Rui Zhang, Rui Liu, Qian Wu, Junjun Li, Xianghua Tang, Bo Xu, Junmei Ding, Nanyu Han and Zunxi Huang

    Citation: BMC Biotechnology 2017 17:37

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