BMC Biotechnology

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Computational modeling of PET tracer distribution in solid tumors integrating microvasculature

Authors: Niloofar Fasaeiyan, M. Soltani, Farshad Moradi Kashkooli, Erfan Taatizadeh and Arman Rahmim

Content type: Research

25 November 2021
Design of a new lyoprotectant increasing freeze-dried Lactobacillus strain survival to long-term storage

Authors: Aurore Bodzen, Audrey Jossier, Sébastien Dupont, Pierre-Yves Mousset, Laurent Beney, Sophie Lafay and Patrick Gervais

Content type: Research

12 November 2021
Optimization of lipase production using fungal isolates from oily residues

Authors: Leticia Miranda Cesário, Giovanna Pinto Pires, Rafael Freitas Santos Pereira, Elisabete Fantuzzi, André da Silva Xavier, Servio Tulio Alves Cassini and Jairo Pinto de Oliveira

Content type: Research

10 November 2021
The mechanism of degradation of alizarin red by a white-rot fungus Trametes gibbosa

Authors: Jian Zhang, Yujie Chi and Lianrong Feng

Content type: Research

5 November 2021
Modification of improved-genome editing via oviductal nucleic acids delivery (i-GONAD)-mediated knock-in in rats

Authors: Takuya Aoshima, Yukari Kobayashi, Hisayoshi Takagi, Kenta Iijima, Masahiro Sato and Shuji Takabayashi

Content type: Research

1 November 2021

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An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

Authors: Huanting Liu and James H Naismith

Content type: Methodology article

4 December 2008
Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

Authors: Frederique Ponchel, Carmel Toomes, Kieran Bransfield, Fong T Leong, Susan H Douglas, Sarah L Field, Sandra M Bell, Valerie Combaret, Alain Puisieux, Alan J Mighell, Philip A Robinson, Chris F Inglehearn, John D Isaacs and Alex F Markham

Content type: Methodology article

13 October 2003
Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies

Authors: Oded Edelheit, Aaron Hanukoglu and Israel Hanukoglu

Content type: Methodology article

30 June 2009
FastCloning: a highly simplified, purification-free, sequence- and ligation-independent PCR cloning method

Authors: Chaokun Li, Aiyun Wen, Benchang Shen, Jia Lu, Yao Huang and Yongchang Chang

Content type: Methodology article

12 October 2011
A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods

Authors: Justin C Yarrow, Zachary E Perlman, Nicholas J Westwood and Timothy J Mitchison

Content type: Methodology article

9 September 2004

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Valuable data often go unpublished when they could be helping to progress science. Hence, the BMC Series introduced Data notes, a short article type allowing you to describe your data and publish them to make your data easier to find, cite and share.

You can publish your data in BMC Genomic Data (genomic, transcriptomic and high-throughput genotype data) or in BMC Research Notes (data from across all natural and clinical sciences).

More information about our unique article type can be found on the BMC Genomic Data and BMC Research Notes journal websites.

New Collections

Genome editing technologies and applications

BMC Biotechnology and BMC Plant Biology together present the latest collection of articles on the advances in genome editing technologies and applications.

Advances in CAR-T immunotherapy

BMC Biotechnology and BMC Cancer together present the latest collection of articles on the advances in CAR-T immunotherapy covering the entire range of advances from lab to clinic.

BMC Series Focus Issues

November: Infection and health

The BMC Series journals would like to dedicate their November focus issue to the recent research into infections and health highlighting four key topics within research on infection - the biology, recent advances in detection and diagnosis, the risk factors and incidence reports and finally on the advances in treatment and combating of infection. Browse the articles in the focus issue further to learn more.

October: Focus on Stem Cells

With Stem Cell Awareness day on the 13th October this year we have compiled an article collection from across different BMC Series journals covering aspects of basic stem cell biology; in vitro differentiation studies; stem-cell based therapy studies for various conditions in animal models; technical advancements and ethical issues.

Lentiviral system for genome editing

In this article the authors demonstrate a new lentivirus-driven method for genome editing of Salmon cells. Read the full article here.

Aims and scope

BMC Biotechnology is an open access, peer-reviewed journal that considers articles on the manipulation of biological macromolecules or organisms for use in experimental procedures, cellular and tissue engineering or in the pharmaceutical, agricultural biotechnology and allied industries.

The journal welcomes submissions in these broad areas of research:
Applied immunology
Cellular, tissue and whole organism biotechnology
Drug discovery and delivery
Environmental biotechnology
Food and nutritional biotechnology
Genetic engineering
Mathematical modeling and statistics in biology
Methods and technological advances in biotechnology
Microbial biotechnology
Plant and agricultural biotechnology
Systems and synthetic biology

To read the full scope of the journal, click here.

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Editor
Akila Sridhar, BioMed Central, UK

Assistant Editor
Lauren McMillan, BioMed Central, UK

BMC Series Blog

Highlights of the BMC Series – October 2021

26 November 2021
Open Data at the BMC Series

29 October 2021
Introducing the BMC Series SDG Editorial Board Members: Maha El Tantawi and Morenike Oluwatoyin Folayan

22 October 2021

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BMC Biotechnology

Articles

Computational modeling of PET tracer distribution in solid tumors integrating microvasculature

Design of a new lyoprotectant increasing freeze-dried Lactobacillus strain survival to long-term storage

Optimization of lipase production using fungal isolates from oily residues

The mechanism of degradation of alizarin red by a white-rot fungus Trametes gibbosa

Modification of improved-genome editing via oviductal nucleic acids delivery (i-GONAD)-mediated knock-in in rats

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies

FastCloning: a highly simplified, purification-free, sequence- and ligation-independent PCR cloning method

A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods