BMC Biotechnology

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Biological modification of pentosans in wheat B starch wastewater and preparation of a composite film

Authors: Piwu Li, Fei Zhao, Xiaofeng Wei, Xiangling Tao and Feng Ding

Content type: Research

17 January 2022
A study on the processing technology for Rhizoma Coptidis

Authors: Yunhong Wang, Weihan Qin, Yujie Yang, Hui Bai, Jirui Wang, Xiaomei Zhang, Yanlei Guo, Lei Hua and Yong Yang

Content type: Research article

14 January 2022
Tenebrio molitor: possible source of polystyrene-degrading bacteria

Authors: Oleen Machona, Farisai Chidzwondo and Rumbidzai Mangoyi

Content type: Research

4 January 2022
Media optimization for SHuffle T7 Escherichia coli expressing SUMO-Lispro proinsulin by response surface methodology

Authors: Aida Bakhshi Khalilvand, Saeed Aminzadeh, Mohammad Hossein Sanati and Fereidoun Mahboudi

Content type: Research

3 January 2022
Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody

Authors: Jialiang Zhao, Jingjing Xu, Tianbin Yang, Xinze Yu, Cheng Cheng, Tong Zhang, Ze Ren, Na Li, Fang Yang and Guiying Li

Content type: Research

20 December 2021

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An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

Authors: Huanting Liu and James H Naismith

Content type: Methodology article

4 December 2008
Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

Authors: Frederique Ponchel, Carmel Toomes, Kieran Bransfield, Fong T Leong, Susan H Douglas, Sarah L Field, Sandra M Bell, Valerie Combaret, Alain Puisieux, Alan J Mighell, Philip A Robinson, Chris F Inglehearn, John D Isaacs and Alex F Markham

Content type: Methodology article

13 October 2003
Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies

Authors: Oded Edelheit, Aaron Hanukoglu and Israel Hanukoglu

Content type: Methodology article

30 June 2009
FastCloning: a highly simplified, purification-free, sequence- and ligation-independent PCR cloning method

Authors: Chaokun Li, Aiyun Wen, Benchang Shen, Jia Lu, Yao Huang and Yongchang Chang

Content type: Methodology article

12 October 2011
A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods

Authors: Justin C Yarrow, Zachary E Perlman, Nicholas J Westwood and Timothy J Mitchison

Content type: Methodology article

9 September 2004

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Valuable data often go unpublished when they could be helping to progress science. Hence, the BMC Series introduced Data notes, a short article type allowing you to describe your data and publish them to make your data easier to find, cite and share.

You can publish your data in BMC Genomic Data (genomic, transcriptomic and high-throughput genotype data) or in BMC Research Notes (data from across all natural and clinical sciences).

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New Collections

Genome editing technologies and applications

BMC Biotechnology and BMC Plant Biology together present the latest collection of articles on the advances in genome editing technologies and applications.

Advances in CAR-T immunotherapy

BMC Biotechnology and BMC Cancer together present the latest collection of articles on the advances in CAR-T immunotherapy covering the entire range of advances from lab to clinic.

BMC Series Focus Issues

January: Antimicrobial resistance

Microbial resistance has become a major threat to human health in the 21st century. In order to provide the public with a general understanding of the situation of drug-resistant pathogens, and to alert and prevent this threat, the BMC Series Journals dedicate their first focus issue in 2022 to research on antimicrobial resistance.

December: HIV

For World AIDS day, the BMC Series Journals dedicate this month's focus issue to research on HIV and AIDS highlighting recent advancements in understanding the biology of the disease, the continued breakthroughs in diagnosis and treatment and also shed some light on what life with HIV is like.

Lentiviral system for genome editing

In this article the authors demonstrate a new lentivirus-driven method for genome editing of Salmon cells. Read the full article here.

Aims and scope

BMC Biotechnology is an open access, peer-reviewed journal that considers articles on the manipulation of biological macromolecules or organisms for use in experimental procedures, cellular and tissue engineering or in the pharmaceutical, agricultural biotechnology and allied industries.

The journal welcomes submissions in these broad areas of research:
Applied immunology
Cellular, tissue and whole organism biotechnology
Drug discovery and delivery
Environmental biotechnology
Food and nutritional biotechnology
Genetic engineering
Mathematical modeling and statistics in biology
Methods and technological advances in biotechnology
Microbial biotechnology
Plant and agricultural biotechnology
Systems and synthetic biology

To read the full scope of the journal, click here.

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BMC Series Blog

Introducing the BMC Series SDG Editorial Board Members: Jarone Lee (2)

20 January 2022
BMC Series Highlights Blog, December 2021

19 January 2022
Introducing the BMC Series SDG Editorial Board Members: Gerald Mboowa

14 January 2022

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BMC Biotechnology

Articles

Biological modification of pentosans in wheat B starch wastewater and preparation of a composite film

A study on the processing technology for Rhizoma Coptidis

Tenebrio molitor: possible source of polystyrene-degrading bacteria

Media optimization for SHuffle T7 Escherichia coli expressing SUMO-Lispro proinsulin by response surface methodology

Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies

FastCloning: a highly simplified, purification-free, sequence- and ligation-independent PCR cloning method

A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods