BMC Biotechnology

Articles

Recent
Most accessed

Analysis of conventional and alternative CRISPR/Cas9 genome editing to enhance a single-base pair knock-in mutation

Authors: Carina Edmondson, Qi Zhou and Xuan Liu

Content type: Research

27 July 2021
Improving the catalytic characteristics of phenolic acid decarboxylase from Bacillus amyloliquefaciens by the engineering of N-terminus and C-terminus

Authors: Qin Li, Ying Xia, Ting Zhao, Yuanyuan Gong, Shangling Fang and Maobin Chen

Content type: Research

26 July 2021
Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis

Authors: Laura Bryan, Michael Henry, Ronan M. Kelly, Christopher C. Frye, Matthew D. Osborne, Martin Clynes and Paula Meleady

Content type: Research

23 July 2021
Lentiviral CRISPR-guided RNA library screening identified Adam17 as an upstream negative regulator of Procr in mammary epithelium

Authors: Ting Wu, Yinghua Wang, Tianxiong Xiao, Yirui Ai, Jinsong Li, Yi Arial Zeng and Qing Cissy Yu

Content type: Research

19 July 2021
Amino terminal recognition by a CCR6 chemokine receptor antibody blocks CCL20 signaling and IL-17 expression via β-arrestin

Authors: Sara Gómez-Melero, Fé Isabel García-Maceira, Tania García-Maceira, Verónica Luna-Guerrero, Gracia Montero-Peñalvo, Isaac Túnez-Fiñana and Elier Paz-Rojas

Content type: Research

5 July 2021

Most recent articles RSS

View all articles

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

Authors: Huanting Liu and James H Naismith

Content type: Methodology article

4 December 2008
Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

Authors: Frederique Ponchel, Carmel Toomes, Kieran Bransfield, Fong T Leong, Susan H Douglas, Sarah L Field, Sandra M Bell, Valerie Combaret, Alain Puisieux, Alan J Mighell, Philip A Robinson, Chris F Inglehearn, John D Isaacs and Alex F Markham

Content type: Methodology article

13 October 2003
Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies

Authors: Oded Edelheit, Aaron Hanukoglu and Israel Hanukoglu

Content type: Methodology article

30 June 2009
A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods

Authors: Justin C Yarrow, Zachary E Perlman, Nicholas J Westwood and Timothy J Mitchison

Content type: Methodology article

9 September 2004
FastCloning: a highly simplified, purification-free, sequence- and ligation-independent PCR cloning method

Authors: Chaokun Li, Aiyun Wen, Benchang Shen, Jia Lu, Yao Huang and Yongchang Chang

Content type: Methodology article

12 October 2011

Most accessed articles RSS

View all articles

Get credit for your data!

New Content Item © © ra2studio

Valuable data often go unpublished when they could be helping to progress science. Hence, the BMC Series introduced Data notes, a short article type allowing you to describe your data and publish them to make your data easier to find, cite and share.

You can publish your data in BMC Genomic Data (genomic, transcriptomic and high-throughput genotype data) or in BMC Research Notes (data from across all natural and clinical sciences).

More information about our unique article type can be found on the BMC Genomic Data and BMC Research Notes journal websites.

New Collections

Genome editing technologies and applications

BMC Biotechnology and BMC Plant Biology together present the latest collection of articles on the advances in genome editing technologies and applications.

Advances in CAR-T immunotherapy

BMC Biotechnology and BMC Cancer together present the latest collection of articles on the advances in CAR-T immunotherapy covering the entire range of advances from lab to clinic.

BMC Series Focus Issues

July: Open data and data sharing

Data are the cornerstones to transparency and reproducibility of research. At the BMC Series, we offer different article types to help you share your data. Explore some of our open access data publications in this focus issue and browse through the additional reading and resources to learn more about this topic.

June: Water and Sanitation.

In celebration of World Environment Day on the 5^th June, the BMC Series presents a focus issue on Water and Sanitation. We have collated open-access content from across our journals to highlight research into clean water, investigating links between water and health and our overall relationship with water.

Lentiviral system for genome editing

In this article the authors demonstrate a new lentivirus-driven method for genome editing of Salmon cells. Read the full article here.

Aims and scope

BMC Biotechnology is an open access, peer-reviewed journal that considers articles on the manipulation of biological macromolecules or organisms for use in experimental procedures, cellular and tissue engineering or in the pharmaceutical, agricultural biotechnology and allied industries.

The journal welcomes submissions in these broad areas of research:
Applied immunology
Cellular, tissue and whole organism biotechnology
Drug discovery and delivery
Environmental biotechnology
Food and nutritional biotechnology
Genetic engineering
Mathematical modeling and statistics in biology
Methods and technological advances in biotechnology
Microbial biotechnology
Plant and agricultural biotechnology
Systems and synthetic biology

To read the full scope of the journal, click here.

@Pixabay

Learn more about the role and requirements here and if interested please complete the accompanying Application form

Editor
Akila Sridhar, BioMed Central, UK

Assistant Editor
Lauren McMillan, BioMed Central, UK

BMC Series Blog

Protecting an investment

16 July 2021
Taking care of the patient- not just the disease

14 July 2021
Call for Papers! Introducing BMC Oral Health’s New Collection titled “Teledentistry and Distance Learning: Improving Access to Oral Health Care and Education”

12 July 2021

Latest Tweets

Your browser needs to have JavaScript enabled to view this timeline

BMC Biotechnology

Articles

Analysis of conventional and alternative CRISPR/Cas9 genome editing to enhance a single-base pair knock-in mutation

Improving the catalytic characteristics of phenolic acid decarboxylase from Bacillus amyloliquefaciens by the engineering of N-terminus and C-terminus

Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis

Lentiviral CRISPR-guided RNA library screening identified Adam17 as an upstream negative regulator of Procr in mammary epithelium

Amino terminal recognition by a CCR6 chemokine receptor antibody blocks CCL20 signaling and IL-17 expression via β-arrestin

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies

A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods

FastCloning: a highly simplified, purification-free, sequence- and ligation-independent PCR cloning method