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  1. Flavonoids are one of the bioactive ingredients of Lonicera macranthoides (L. macranthoides), however, their biosynthesis in the flower is still unclear. In this study, combined transcriptomic and targeted metabo...

    Authors: Ling Ling Lv, Li Yun Li, Long Qian Xiao and Jian Hui Pi
    Citation: BMC Biotechnology 2024 24:19
  2. Nanotechnology-based drug delivery systems have received much attention over the past decade. In the present study, we synthesized Methyl Urolithin A-loaded solid lipid nanoparticles decorated with the folic a...

    Authors: Ilham Naeem Abd Ali Al-Fatlawi, Vahid Pouresmaeil, Fatemeh Davoodi-Dehaghani, Aida Pouresmaeil, Ali Akhtari and Masoud Homayouni Tabrizi
    Citation: BMC Biotechnology 2024 24:18
  3. Thermostable DNA polymerases, such as Taq isolated from the thermophilic bacterium Thermus aquaticus, enable one-pot exponential DNA amplification known as polymerase chain reaction (PCR). However, properties oth...

    Authors: Cristina Hernández-Rollán, Anja K. Ehrmann, Arsenios Vlassis, Vijayalakshmi Kandasamy and Morten H. H. Nørholm
    Citation: BMC Biotechnology 2024 24:17
  4. Cancer associated drug resistance is a major cause for cancer aggravation, particularly as conventional therapies have presented limited efficiency, low specificity, resulting in long term deleterious side eff...

    Authors: Mona Elradi, Ahmed I. Ahmed, Ahmed M. Saleh, Khaled M. A. Abdel-Raouf, Lina Berika, Yara Daoud and Asma Amleh
    Citation: BMC Biotechnology 2024 24:14
  5. Smoking was a major risk factor for chronic obstructive pulmonary disease (COPD). This study plan to explore the mechanism of Polyphyllin B in lung injury induced by cigarette smoke (CSE) in COPD.

    Authors: Qing Wang, Zhiyi He, Jinqi Zhu, Mengyun Hu, Liu Yang and Hongzhong Yang
    Citation: BMC Biotechnology 2024 24:13
  6. The objective of this study was to establish a methodology for determining carboxymethyl lysine (CML) and carboxyethyl lysine (CEL) concentrations in human plasma using liquid chromatography-tandem mass spectr...

    Authors: Daguang Wang, Junshan Wang, Xinghong Liu, Kehe Du, Hongjun Liu, Xiaofeng Yang, Tianyi Liu, Qian Liu, Meng Wang and Jian Guo
    Citation: BMC Biotechnology 2024 24:12
  7. One of the current challenges is to secure wheat crop production to meet the increasing global food demand and to face the increase in its purchasing power. Therefore, the current study aimed to exploit a new ...

    Authors: Nashwa H. Abdullah, Nouran A. Elbialy, Mohamed Abdelnaser Amer, Mostafa Kh. Gabr, Amira Salah El-Din Youssef, Mohamed H. Sharaf, M. E. Shehata, Mohamed H. Kalaba and Elham R. S. Soliman
    Citation: BMC Biotechnology 2024 24:11
  8. Polymicrobial communities lead to worsen the wound infections, due to mixed biofilms, increased antibiotic resistance, and altered virulence production. Promising approaches, including enzymes, may overcome th...

    Authors: Sanaz Dehbashi, Hamed Tahmasebi, Mohammad Yousef Alikhani, Mohammad-Ali Shahbazi and Mohammad Reza Arabestani
    Citation: BMC Biotechnology 2024 24:10
  9. The production of Pleurotus ostreatus mycelium as a promising object for use in food and other industries is hampered by a lack of information about the strain-specificity of this fungus mycelium growth and its a...

    Authors: Tetiana Krupodorova, Victor Barshteyn, Victoria Tsygankova, Mustafa Sevindik and Yaroslav Blume
    Citation: BMC Biotechnology 2024 24:9
  10. Silver nanoparticles (Ag-NPs) have a unique mode of action as antibacterial agents in addition to their anticancer and antioxidant properties. In this study, microbial nanotechnology is employed to synthesize ...

    Authors: Mohamed T. Shaaban, Briksam S. Mohamed, Muhammad Zayed and Sabha M. El-Sabbagh
    Citation: BMC Biotechnology 2024 24:8
  11. The Mediterranean fruit fly, Ceratitis capitata, is a significant agricultural pest managed through area-wide integrated pest management (AW-IPM) including a sterile insect technique (SIT) component. Male-only re...

    Authors: Germano Sollazzo, Katerina Nikolouli, Georgia Gouvi, Roswitha A. Aumann, Marc F. Schetelig and Kostas Bourtzis
    Citation: BMC Biotechnology 2024 24:7
  12. L-arginase, is a powerful anticancer that hydrolyzes L-arginine to L-ornithine and urea. This enzyme is widely distributed and expressed in organisms like plants, fungi, however very scarce from bacteria. Our ...

    Authors: Manal S. Selim, Marwa M. Mounier, Sayeda A. Abdelhamid, Ahmed Abdelghani Hamed, Mostafa M. Abo Elsoud and Sahar S. Mohamed
    Citation: BMC Biotechnology 2024 24:6
  13. Modern high-throughput technologies enable the processing of a large number of samples simultaneously, while also providing rapid and accurate procedures. In recent years, automated liquid handling workstation...

    Authors: Giovanni Annona, Assunta Liberti, Carla Pollastro, Antonietta Spagnuolo, Paolo Sordino and Pasquale De Luca
    Citation: BMC Biotechnology 2024 24:4
  14. The growing spread of infectious diseases has become a potential global health threat to human beings. According to WHO reports, in this study, we investigated the impact of co-cultivating the isolated endophy...

    Authors: Ahmed A. Hamed, Mosad A. Ghareeb, Ayda K. Kelany, Mohamed Abdelraof, Hoda A. Kabary, Nariman R. Soliman and Mohamed E. Elawady
    Citation: BMC Biotechnology 2024 24:3
  15. Lytic polysaccharide monooxygenases (LPMOs) catalyzing the oxidative cleavage of different types of polysaccharides have potential to be used in various industries. However, AA13 family LPMOs which specificall...

    Authors: Meijuan Zhang, Xiaoping Fu, Rongrong Gu, Bohua Zhao, Xingya Zhao, Hui Song, Hongchen Zheng, Jianyong Xu and Wenqin Bai
    Citation: BMC Biotechnology 2024 24:2
  16. The chimeric antigen receptor-expressing T (CAR-T) cells for cancer immunotherapy have obtained considerable clinical importance. CAR T cells need an optimized intracellular signaling domain to get appropriate...

    Authors: Fatemeh Hajari Taheri, Mahmoud Hassani, Zahra Sharifzadeh, Mahdi Behdani, Shahryar Abdoli, Mahtab Sayadi, Kowsar Bagherzadeh, Arash Arashkia and Mohsen Abolhassani
    Citation: BMC Biotechnology 2024 24:1
  17. In tissue engineering (TE) and regenerative medicine, the accessibility of engineered scaffolds that modulate inflammatory states is extremely necessary. The aim of the current work was to assess the efficacy ...

    Authors: Akram Firouzi Amandi, Seyed Abbas Shahrtash, Shaylan Kalavi, Afshin Moliani, Hanieh Mousazadeh, Mehdi Rezai Seghin Sara and Mehdi Dadashpour
    Citation: BMC Biotechnology 2023 23:55
  18. Probiotics are viable microorganisms that when administered in adequate amounts confer health benefits to the host. In fish, probiotic administration has improved growth, and immunological parameters. For this...

    Authors: Marcelo Fernando Valle-Vargas, Ruth Yolanda Ruiz-Pardo, Luisa Villamil-Díaz and María Ximena Quintanilla-Carvajal
    Citation: BMC Biotechnology 2023 23:54
  19. Vitamin B12 (VB12) has a wide range of applications and high economic value. In this study, a new strain with high VB12 production potential, Ensifer adhaerens S305, was identified in sewage. Because E. adhaerens

    Authors: Yongheng Liu, Wei Huang, Qi Wang, Cilang Ma, Yongyong Chang and Jianyu Su
    Citation: BMC Biotechnology 2023 23:53
  20. In this study, we designed a novel genetic circuit sensitive to Cd2+, Zn2+ and Pb2+ by mimicking the CadA/CadR operon system mediated heavy metal homeostasis mechanism of Pseudomonas aeruginosa. The regular DNA m...

    Authors: H. M. L. P. B. Herath, W. R. M. de Silva, R. S. Dassanayake, Y. I. N. S. Gunawardene, J. R. P. Jayasingha, M. K. Gayashan, L. O. B. Afonso and K. M. N. de Silva
    Citation: BMC Biotechnology 2023 23:52
  21. Goat rumen microbial communities are perceived as one of the most potential biochemical reservoirs of multi-functional enzymes, which are applicable to enhance wide array of bioprocesses such as the hydrolysis...

    Authors: Santosh Thapa, Suping Zhou, Joshua O’Hair, Kamal Al Nasr, Alexander Ropelewski and Hui Li
    Citation: BMC Biotechnology 2023 23:51
  22. Filamentous fungi are efficient degraders of plant biomass and the primary producers of commercial cellulolytic enzymes. While the transcriptional regulation mechanisms of cellulases have been continuously exp...

    Authors: Fanglei Xue, Zhen Zhao, Shuying Gu, Meixin Chen, Jing Xu, Xuegang Luo, Jingen Li and Chaoguang Tian
    Citation: BMC Biotechnology 2023 23:50
  23. A lot of kitchen waste oil is produced every day worldwide, leading to serious environmental pollution. As one of the environmental protection methods, microorganisms are widely used treating of various wastes...

    Authors: Xinran Duan, Wei Zhai, Xintian Li, Sicheng Wu, Ye Wang, Lixia Wang, Wangdui Basang, Yanbin Zhu and Yunhang Gao
    Citation: BMC Biotechnology 2023 23:48
  24. γ-polyglutamic acid (γ-PGA) is a biomarker that can be directly obtained by microbial fermentation. Poly(amino acid) superabsorbent polymers (SAPs) were prepared with purified γ-PGA as raw material and ethylen...

    Authors: Zhao Jianbo, Wei Jun, Wang Xuanlin and Cao Hui
    Citation: BMC Biotechnology 2023 23:47
  25. Brucellosis remains one of the global health concerns that reemerges in recent years. Delayed or inaccurate diagnosis end to a long treatment duration and financial burden; therefore, finding a good antigen fo...

    Authors: M. Golchin, S. Mollayi, E. Mohammadi and N. Eskandarzade
    Citation: BMC Biotechnology 2023 23:46
  26. Target identification is an essential part of the drug discovery and development process, and its efficacy plays a crucial role in the success of any given therapy. Although protein target identification resea...

    Authors: Yasser Tabana, Dinesh Babu, Richard Fahlman, Arno G. Siraki and Khaled Barakat
    Citation: BMC Biotechnology 2023 23:44
  27. The major safety concern of the clinical application of wild type FGF19 (FGF19WT) emerges given that its extended treatment causes hepatocellular carcinoma. Therefore, we previously generated a safer FGF19 varian...

    Authors: Lu Shi, Tiantian Zhao, Lei Huang, Xiaomin Pan, Tianzhen Wu, Xin Feng, Taoli Chen, Jiamin Wu and Jianlou Niu
    Citation: BMC Biotechnology 2023 23:43
  28. Helicobacter pylori cause a variety of gastric malignancies, gastric ulcers, and cause erosive diseases. The extreme nature of the bacterium and the implantation of this bacterium protects it against designing a ...

    Authors: Zahra Ahmadzadeh Chaleshtori, Ali Asghar Rastegari, Hashem Nayeri and Abbas Doosti
    Citation: BMC Biotechnology 2023 23:42
  29. Metal nanoparticles exhibit excellent antifungal abilities and are seen as a good substitute for controlling different kinds of fungi. Of all known taxa, cyanobacteria have received significant consideration a...

    Authors: Bahareh Nowruzi, Bilal Saad Jalil and James S Metcalf
    Citation: BMC Biotechnology 2023 23:41
  30. Cutaneotrichosporon oleaginosus is an oleaginous yeast that can produce up to 80% lipid per dry weight. Its high capacity for the biosynthesis of single cell oil makes it highly interesting for the production of ...

    Authors: Nikolaus I. Stellner, Zora S. Rerop, Norbert Mehlmer, Mahmoud Masri, Marion Ringel and Thomas B. Brück
    Citation: BMC Biotechnology 2023 23:40
  31. Staphylococcus aureus is a unique challenge for the healthcare system because it can form biofilms, is resistant to the host's immune system, and is resistant to numerous antimicrobial therapies. The aim of this ...

    Authors: Ellahe Nouruzi, Seyed Mostafa Hosseini, Babak Asghari, Reza Mahjoub, Ehsan Nazarzadeh Zare, Mohammad-Ali Shahbazi, Fereshte Kalhori and Mohammad Reza Arabestani
    Citation: BMC Biotechnology 2023 23:39
  32. Cartilage defects are common sports injuries without significant treatment. Articular cartilage with inferior regenerative potential resulted in the poor formation of hyaline cartilage in defects. Acellular ma...

    Authors: Huiming Jiang, Jun Lu, Jiawei Li, Zizheng Liu, Fufei Chen, Rui Wu, Xingquan Xu, Yuan Liu, Yiqiu Jiang and Dongquan Shi
    Citation: BMC Biotechnology 2023 23:38
  33. Classical swine fever (CSF) is a fatal contagious disease affecting pigs caused by classical swine fever virus (CSFV). The disease can be transmitted by pigs and wild boars, and it is difficult to prevent and ...

    Authors: Riai Okamoto, Nobumasa Ito, Yutaro Ide, Bouchra Kitab, Yoshihiro Sakoda and Kyoko Tsukiyama-Kohara
    Citation: BMC Biotechnology 2023 23:37
  34. Lamotrigine is an effective antiseizure medication that can be used in the management of focal and generalized epilepsies in pediatric patients. This study was conducted to quantify and compare the solubility ...

    Authors: Ramzi Shawahna, Hala Saba’aneh, Amal Daraghmeh, Yara Qassarwi, Valentina Franco and Xavier Declèves
    Citation: BMC Biotechnology 2023 23:36
  35. Biofuel research that aims to optimize growth conditions in microalgae is critically important. Chlamydomonas reinhardtii is a green microalga that offers advantages for biofuel production research. This study co...

    Authors: David I. Gonzalez and Ruby A. Ynalvez
    Citation: BMC Biotechnology 2023 23:35
  36. Currently, Aspergillus terreus is used for the industrial production of itaconic acid. Although, alternative feedstock use in fermentations is crucial for cost-efficient and sustainable itaconic acid production, ...

    Authors: Paul-Joachim Niehoff, Waldemar Müller, Johannes Pastoors, Katharina Miebach, Philipp Ernst, Johannes Hemmerich, Stephan Noack, Nick Wierckx and Jochen Büchs
    Citation: BMC Biotechnology 2023 23:34
  37. Dopamine is high-value compound of pharmaceutical interest, but its industrial scale production mostly focuses on chemical synthesis, possessing environment pollution. Bio-manufacturing has caused much attenti...

    Authors: Siyuan Gao, Ding Ma, Yongtao Wang, Alei Zhang, Xin Wang and Kequan Chen
    Citation: BMC Biotechnology 2023 23:33
  38. Global efforts to characterize diseases of poverty are hampered by lack of affordable and comprehensive detection platforms, resulting in suboptimal allocation of health care resources and inefficient disease ...

    Authors: Iván Hernández-Neuta, Anastasia Magoulopoulou, Flor Pineiro, Jan Gorm Lisby, Mats Gulberg and Mats Nilsson
    Citation: BMC Biotechnology 2023 23:31
  39. Carbohydrate antigen 724 (CA724) is a sensitive and specific indicator for multiple malignant tumors. The aim of this study was to establish a Eu-time resolved fluorescence immunochromatography (Eu-TRFICO) met...

    Authors: Chang Liu, Cuicui Chen, Fenglan Peng, Huankun Liang, Shuhai Zhong, Tiancai Liu, Laiqing Li, Alexander Boronin and Wenqi Dong
    Citation: BMC Biotechnology 2023 23:30
  40. Porcine fetal fibroblasts (PFFs) are important donor cells for generating genetically modified pigs, but the transfection efficiencies of PFFs are often unsatisfactory especially when large-size vectors are to...

    Authors: Weiwei Liu, Xiaoguo Wang, Ruirong Liu, Yaya Liao, Zhiwei Peng, Haoyun Jiang, Qiqi Jing and Yuyun Xing
    Citation: BMC Biotechnology 2023 23:29
  41. Coelomic fluid, a pharmacologically active compound in earthworms, exhibits a range of biological activities, including antioxidant, anti-inflammatory, and anticancer. However, the biological activities exerte...

    Authors: Asmaa E. Farouk, Sohair R. Fahmy, Amel M. Soliman, Sherif Abdelaziz Ibrahim and Shimaa A. Sadek
    Citation: BMC Biotechnology 2023 23:28
  42. Optimization of indirect shoot regeneration protocols is one of the key prerequisites for the development of Agrobacterium-mediated genetic transformation and/or genome editing in Passiflora caerulea. Comprehensi...

    Authors: Marziyeh Jafari and Mohammad Hosein Daneshvar
    Citation: BMC Biotechnology 2023 23:27
  43. Oxford Nanopore sequencing technology (ONT) is currently widely used due to its affordability, simplicity, and reliability. Despite the advantage ONT has over next-generation sequencing in detecting resistance...

    Authors: Hussain A. Safar, Fatemah Alatar, Kother Nasser, Rehab Al-Ajmi, Wadha Alfouzan and Abu Salim Mustafa
    Citation: BMC Biotechnology 2023 23:26

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