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Methodology article
Genetically modified crops (GM crops) have been developed to improve the agricultural traits of modern crop cultivars. Safety assessments of GM crops are of paramount importance in research at developmental st...
BMC Biotechnology 2017 17:67
Published on: 15 August 2017
Research article
Phloroglucinol is an important chemical, and the biosynthesis processes which can convert glucose to phloroglucinol have been established. However, due to approximate 80% of the glucose being transformed into ...
BMC Biotechnology 2017 17:66
Published on: 8 August 2017
Research article
Umbilical cord blood provides a source of hematopoietic stem cells for transplantation with immunological and availability advantages over conventional bone marrow sources. Limited cell numbers and slower engr...
BMC Biotechnology 2017 17:65
Published on: 4 August 2017
Research article
Development of chimeric Cry toxins by protein engineering of known and validated proteins is imperative for enhancing the efficacy and broadening the insecticidal spectrum of these genes. Expression of novel C...
BMC Biotechnology 2017 17:64
Published on: 2 August 2017
Research article
Acetic acid is a predominant by-product of lignocellulosic biofuel process, which inhibits microbial biocatalysts. Development of bacterial strains that are tolerant to acetic acid is challenging due to poor u...
BMC Biotechnology 2017 17:63
Published on: 1 August 2017
Methodology article
Direct manipulation of the genome is a widespread technique for genetic studies and synthetic biology applications. The tyrosine and serine site-specific recombination systems of bacteriophages HK022 and ΦC31 ...
BMC Biotechnology 2017 17:62
Published on: 14 July 2017
Methodology article
The T-cell receptor (TCR), located on the surface of T cells, is responsible for the recognition of the antigen-major histocompatibility complex, leading to the initiation of an inflammatory response. Analysin...
BMC Biotechnology 2017 17:61
Published on: 10 July 2017
Research article
Dissolved oxygen tension (DOT) is hardly constant and homogenously distributed in a bioreactor, which can have a negative impact in the metabolism and product synthesis. However, the effects of DOT on plasmid ...
BMC Biotechnology 2017 17:60
Published on: 4 July 2017
Research article
The environmental gliding bacteria Lysobacter are emerging as a new group of biocontrol agents due to their prolific production of lytic enzymes and potent antibiotic natural products. These bacteria are intrinsi...
BMC Biotechnology 2017 17:59
Published on: 4 July 2017
Research article
Fibroblast growth factor 21 (FGF21) is an endocrine-acting hormone that has the potential to treat diabetic nephropathy. However, development of FGF21 into a therapeutic has been hindered due to its low intrin...
BMC Biotechnology 2017 17:58
Published on: 4 July 2017
Research article
Fas ligand plays a key role in the human immune system as a major cell death inducing protein. The extracellular domain of human Fas ligand (hFasLECD) triggers apoptosis of malignant cells, and therefore is ex...
BMC Biotechnology 2017 17:56
Published on: 3 July 2017
Research article
Effective and simple methods that lead to higher enzymatic efficiencies are highly sough. Here we proposed a foldon-triggered trimerization of the target enzymes with significantly improved catalytic performan...
BMC Biotechnology 2017 17:57
Published on: 3 July 2017
Research Article
Xylanase degrades xylan into monomers of various sizes by catalyzing the endohydrolysis of the 1,4-β-D-xylosidic linkage randomly, possessing potential in wide industrial applications. Most of xylanases are su...
BMC Biotechnology 2017 17:55
Published on: 21 June 2017
Methodology article
Three-dimensional (3D) spheroids are frequently used in toxicological study because their morphology and function closely resemble those of tissue. As these properties are maintained over a long term, repeated...
BMC Biotechnology 2017 17:54
Published on: 20 June 2017
Research article
Alpha amylase hydrolyzes α-bonds of polysaccharides such as starch and produces malto-oligosaccharides. Its starch saccharification applications make it an essential enzyme in the textile, food and brewing ind...
BMC Biotechnology 2017 17:53
Published on: 19 June 2017
Research article
Cotton fiber, a natural fiber widely used in the textile industry, is differentiated from single cell of ovule epidermis. A large number of genes are believed to be involved in fiber formation, but so far only...
BMC Biotechnology 2017 17:50
Published on: 12 June 2017
Research article
The discharge of poorly treated effluents into the environment has far reaching, consequential impacts on human and aquatic life forms. Thus, we evaluated the flocculating efficiency of our test bioflocculant ...
BMC Biotechnology 2017 17:51
Published on: 12 June 2017
Research article
The Gaussia princeps luciferase is used as a stand-alone reporter of transgene expression for in vitro and in vivo expression systems due to the rapid and easy monitoring of luciferase activity. We sought to simu...
BMC Biotechnology 2017 17:52
Published on: 12 June 2017
Research article
Somatic cell selection in plants allows the recovery of spontaneous mutants from cell cultures. When coupled with the regeneration of plants it allows an effective approach for the recovery of novel traits in ...
BMC Biotechnology 2017 17:49
Published on: 6 June 2017
Research article
Whey permeate is a lactose-rich effluent remaining after protein extraction from milk-resulting cheese whey, an abundant dairy waste. The lactose to ethanol fermentation can complete whey valorization chain by...
BMC Biotechnology 2017 17:48
Published on: 2 June 2017
Research article
Bluetongue is a disease of domestic and wild ruminants caused by bluetongue virus serotypes (BTV), which have caused serious outbreaks worldwide. Commercially available vaccines are live-attenuated or inactiva...
BMC Biotechnology 2017 17:47
Published on: 30 May 2017
Research article
Traditional submerged fermentation mainly accumulates intracellular orange pigments with absorption maxima at 470 nm, whereas extractive fermentation of Monascus spp. with Triton X-100 can promote the export of i...
BMC Biotechnology 2017 17:46
Published on: 25 May 2017
Research article
Ultrasound and microbubbles (USMB) have been shown to enhance the intracellular uptake of molecules, generally thought to occur as a result of sonoporation. The underlying mechanism associated with USMB-enhanc...
BMC Biotechnology 2017 17:45
Published on: 18 May 2017
Research article
Endo-xylanases are essential in degrading hemicellulose of various lignocellulosic substrates. Hemicellulose degradation by Geobacillus spp. is facilitated by the hemicellulose utilization (HUS) locus that is pre...
BMC Biotechnology 2017 17:44
Published on: 18 May 2017
Methodology article
Targeted delivery of gene therapy vectors to the mouse respiratory tract is often performed via intranasal or intratracheal administration; however, there can be a great deal of variability between these metho...
BMC Biotechnology 2017 17:43
Published on: 15 May 2017
