Kaminuma O, Mori A, Suko M, Kikkawa H, Naito K, Okudaira H: Development of lung eosinophilic inflammation by the infusion of IL-5-producing T cell clones. International Archives of Allergy and Immunology. 1997, 114: 10-13.
Article
CAS
Google Scholar
Hamelmann E, Cieslewicz G, Schwarze J, Ishizuka T, Joetham A, Heusser C, et al: Anti-interleukin 5 but not Anti-IgE prevents airway inflammation and airway hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine. 1999, 160: 934-941.
Article
CAS
Google Scholar
Blumchen K, Kallinich T, Hamelmann E: Interleukin-5: a novel target for asthma therapy. Expert Opinion on Biological Therapy. 2001, 1: 433-453.
Article
CAS
Google Scholar
Bachert C, Wagenmann M, Hauser U, Rudack C: IL-5 synthesis is upregulated in human nasal polyp tissue. Journal of Allergy and Clinical Immunology. 1997, 99: 837-842.
Article
CAS
Google Scholar
Denburg JA: Haemopoietic mechanisms in nasal polyposis and asthma. Thorax. 2000, 55: S24-S25. 10.1136/thorax.55.suppl_2.S24.
Article
Google Scholar
Rizzo CA, Yang R, Greenfeder S, Egan RW, Pauwels RA, Hey JA: The IL-5 receptor on human bronchus selectively primes for hyperresponsiveness. Journal of Allergy and Clinical Immunology. 2002, 109: 404-409. 10.1067/mai.2002.122459.
Article
CAS
Google Scholar
Bazan JF: Structural Design and Molecular Evolution of A Cytokine Receptor Superfamily. Proceedings of the National Academy of Sciences of the United States of America. 1990, 87: 6934-6938.
Article
CAS
Google Scholar
Boulay JL, Paul WE: The Interleukin-4 Family of Lymphokines. Current Opinion in Immunology. 1992, 4: 294-298. 10.1016/0952-7915(92)90079-T.
Article
CAS
Google Scholar
Takagi M, Hara T, Ichihara M, Takatsu K, Miyajima A: Multi-Colony Stimulating Activity of Interleukin-5 (Il-5) on Hematopoietic Progenitors from Transgenic Mice That Express Il-5 Receptor Ex Subunit Constitutively. Journal of Experimental Medicine. 1995, 181: 889-899.
Article
CAS
Google Scholar
Denburg JA, Silver JE, Abrams JS: Interleukin-5 Is A Human Basophilopoietin – Induction of Histamine Content and Basophilic Differentiation of Hl-60 Cells and of Peripheral-Blood Basophil-Eosinophil Progenitors. Blood. 1991, 77: 1462-1468.
CAS
Google Scholar
Migita M, Yamaguchi N, Mita S, Higuchi S, Hitoshi Y, Yoshida Y, et al: Characterization of the Human Il-5 Receptors on Eosinophils. Cellular Immunology. 1991, 133: 484-497.
Article
CAS
Google Scholar
Miyajima A, Mui ALF, Ogorochi T, Sakamaki K: Receptors for Granulocyte-Macrophage Colony-Stimulating Factor, Interleukin-3, and Interleukin-5. Blood. 1993, 82: 1960-1974.
CAS
Google Scholar
Tuypens T, Tavernier J: Genomic Organization of the hIL-5R Gene. Faseb Journal. 1992, 6: A1896-
Google Scholar
Tavernier J, Van der Heyden J, Verhee A, Brusselle G, Van Ostade X, Vandekerckhove J, et al: Interleukin 5 regulates the isoform expression of its own receptor alpha-subunit. Blood. 2000, 95: 1600-1607.
CAS
Google Scholar
Tavernier J, Tuypens T, Plaetinck G, Verhee A, Fiers W, Devos R: Molecular-Basis of the Membrane-Anchored and 2 Soluble Isoforms of the Human Interleukin-5 Receptor Alpha-Subunit. Proceedings of the National Academy of Sciences of the United States of America. 1992, 89: 7041-7045.
Article
CAS
Google Scholar
Yasruel Z, Humbert M, Kotsimbos TC, Ploysongsang Y, Minshall E, Durham SR, et al: Membrane-bound and soluble alpha IL-5 receptor mRNA in the bronchial mucosa of atopic and nonatopic asthmatics. American Journal of Respiratory and Critical Care Medicine. 1997, 155: 1413-1418.
Article
CAS
Google Scholar
Koike M, Takatsu K: Il-5 and Its Receptor – Which Role do they play in the Immune-Response. International Archives of Allergy and Immunology. 1994, 104: 1-9.
Article
CAS
Google Scholar
Tavernier J, Devos R, Cornelis S, Tuypens T, Vanderheyden J, Fiers W, et al: A Human High-Affinity Interleukin-5 Receptor (IL5R) Is Composed of An IL5-Specific Alpha-Chain and a Beta-Chain Shared with the Receptor for Gm-Csf. Cell. 1991, 66: 1175-1184.
Article
CAS
Google Scholar
Monahan J, Siegel N, Keith R, Caparon M, Christine L, Compton R, et al: Attenuation of IL-5-mediated signal transduction, eosinophil survival, and inflammatory mediator release by a soluble human IL-5 receptor. Journal of Immunology. 1997, 159: 4024-4034.
CAS
Google Scholar
Zanders E: Interleukin-5 Receptor-Alpha Chain Messenger-RNA Is Down-Regulated by Transforming Growth-Factor-Beta-1. European Cytokine Network. 1994, 5: 422-
Google Scholar
Devos R, Plaetinck G, Cornelis S, Guisez Y, Van der Heyden J, Tavernier J: Interleukin-5 and its receptor: a drug target for eosinophilia associated with chronic allergic disease. Journal of Leukocyte Biology. 1995, 57: 813-
CAS
Google Scholar
Yin JL, Shackel NA, Zekry A, McGuinness PH, Richards C, Van der Putten K, et al: Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for measurement of cytokine and growth factor mRNA expression with fluorogenic probes or SYBR Green I. Immunology and Cell Biology. 2001, 79: 213-221. 10.1046/j.1440-1711.2001.01002.x.
Article
CAS
Google Scholar
Bustin SA: Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. Journal of Molecular Endocrinology. 2000, 25: 169-193.
Article
CAS
Google Scholar
Higuchi R, Fockler C, Dollinger G, Watson R: Kinetic Pcr Analysis – Real-Time Monitoring of DNA Amplification Reactions. Bio-Technology. 1993, 11: 1026-1030.
Article
CAS
Google Scholar
Morrison TB, Weis JJ, Wittwer CT: Quantification of low-copy transcripts by continuous SYBR (R) green I monitoring during amplification. Biotechniques. 1998, 24: 954-
CAS
Google Scholar
Livak KJ, Flood SJA, Marmaro J, Giusti W, Deetz K: Oligonucleotides with Fluorescent Dyes at Opposite Ends Provide A Quenched Probe System Useful for Detecting PCR Product and Nucleic-Acid Hybridization. Pcr-Methods and Applications. 1995, 4: 357-362.
Article
CAS
Google Scholar
Wittwer CT, Herrmann MG, Moss AA, Rasmussen RP: Continuous fluorescence monitoring of rapid cycle DNA amplification. Biotechniques. 1997, 22: 130-
CAS
Google Scholar
Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, et al: Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002, 3: RESEARCH0034.1-0034.11. 10.1186/gb-2002-3-7-research0034.
Article
Google Scholar
Vandenbroucke II, Vandesompele J, Paepe AD, Messiaen L: Quantification of splice variants using real-time PCR. Nucleic Acids Res. 2001, 29: E68-10.1093/nar/29.13.e68.
Article
CAS
Google Scholar
Simon HU, Yousefi S, Schranz C, Schapowal A, Bachert C, Blaser K: Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia. J Immunol. 1997, 158: 3902-3908.
CAS
Google Scholar
Liu LY, Sedgwick JB, Bates ME, Vrtis RF, Gern JE, Kita H, et al: Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge. J Immunol. 2002, 169: 6452-6458.
Article
CAS
Google Scholar
Gevaert P, Bachert C, Holtappels G, Novo CP, Van Der HJ, Fransen L, et al: Enhanced soluble interleukin-5 receptor alpha expression in chronic rhinosinusitis. Allergy. 2003, 58: 371-379.
Article
CAS
Google Scholar
Leckie MJ, ten Brinke A, Khan J, Diamant Z, O'Connor BJ, Walls CM, et al: Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet. 2000, 356: 2144-2148. 10.1016/S0140-6736(00)03496-6.
Article
CAS
Google Scholar