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  1. To maintain populations of microbial cells under controlled conditions of growth and environment for an indefinite duration is a prerequisite for experimentally evolving natural isolates of wild-type species o...

    Authors: Valérie A de Crécy-Lagard, Jacques Bellalou, Rupert Mutzel and Philippe Marlière

    Citation: BMC Biotechnology 2001 1:10

    Content type: Methodology article

    Published on:

  2. Modern drug discovery is concerned with identification and validation of novel protein targets from among the 30,000 genes or more postulated to be present in the human genome. While protein-protein interactio...

    Authors: Renuka C Pillutla, Ku-chuan Hsiao, Renee Brissette, Paul S Eder, Tony Giordano, Paul W Fletcher, Michael Lennick, Arthur J Blume and Neil I Goldstein

    Citation: BMC Biotechnology 2001 1:6

    Content type: Research article

    Published on:

  3. There have been many attempts to develop new materials with stability and high affinity towards immunoglobulins. Some of glycolipids such as gangliosides exhibit a high affinity toward immunoglobulins. However...

    Authors: Jae Hong Im, Takashi Nakane, Hiroshi Yanagishita, Toru Ikegami and Dai Kitamoto

    Citation: BMC Biotechnology 2001 1:5

    Content type: Research article

    Published on:

  4. Hydrophobic polystyrene is the most common material for solid phase immunoassay. Proteins are immobilized on polystyrene by passive adsorption, which often causes considerable denaturation. Biological macromol...

    Authors: Vadim V Shmanai, Tamara A Nikolayeva, Ludmila G Vinokurova and Anatoli A Litoshka

    Citation: BMC Biotechnology 2001 1:4

    Content type: Research article

    Published on:

  5. The Gavac™ vaccine against the cattle tick Boophilus microplus has proven its efficacy in a large number of controlled and field experiments. However, this vaccine could be further improved by searching for new a...

    Authors: Manuel Rodríguez Valle, Carlos Montero, Héctor Machado and Marisdania Joglar

    Citation: BMC Biotechnology 2001 1:2

    Content type: Research article

    Published on:

  6. Infections of bacterial cultures by bacteriophages are serious problems in biotechnological laboratories. Apart from such infections, prophage induction in the host cells may also be dangerous. Escherichia coli i...

    Authors: Agata Czyz, Marcin Los, Borys Wrobel and Grzegorz Wegrzyn

    Citation: BMC Biotechnology 2001 1:1

    Content type: Methodology article

    Published on:

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