Cabantous S, Terwilliger TC, Waldo GS: Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein. Nat Biotechnol. 2005, 23: 102-107. 10.1038/nbt1044.
Article
CAS
Google Scholar
Paulmurugan R, Gambhir SS: An intramolecular folding sensor for imaging estrogen receptor-ligand interactions. Proc Natl Acad Sci USA. 2006, 103: 15883-15888. 10.1073/pnas.0607385103.
Article
CAS
Google Scholar
Ostermeier M: Engineering allosteric protein switches by domain insertion. Protein Eng Des Sel. 2005, 18: 359-364. 10.1093/protein/gzi048.
Article
CAS
Google Scholar
Dueber JE, Yeh BJ, Chak K, Lim WA: Reprogramming control of an allosteric signaling switch through modular recombination. Science. 2003, 301: 1904-1908. 10.1126/science.1085945.
Article
CAS
Google Scholar
Guntas G, Mansell TJ, Kim JR, Ostermeier M: Directed evolution of protein switches and their application to the creation of ligand-binding proteins. Proc Natl Acad Sci USA. 2005, 102: 11224-11229. 10.1073/pnas.0502673102.
Article
CAS
Google Scholar
Gloriam DE, Fredriksson R, Schioth HB: The G protein-coupled receptor subset of the rat genome. BMC Genomics. 2007, 8: 338-10.1186/1471-2164-8-338.
Article
Google Scholar
Haitina T, Fredriksson R, Foord SM, Schioth HB, Gloriam DE: The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents. BMC Genomics. 2009, 10: 24-10.1186/1471-2164-10-24.
Article
Google Scholar
Quignon P, Giraud M, Rimbault M, Lavigne P, Tacher S, Morin E, Retout E, Valin AS, Lindblad-Toh K, Nicolas J, Galibert F: The dog and rat olfactory receptor repertoires. Genome Biol. 2005, 6: R83-10.1186/gb-2005-6-10-r83.
Article
Google Scholar
Gilchrist A: Modulating G-protein-coupled receptors: from traditional pharmacology to allosterics. Trends Pharmacol Sci. 2007, 28: 431-437. 10.1016/j.tips.2007.06.012.
Article
CAS
Google Scholar
Versele M, Lemaire K, Thevelein JM: Sex and sugar in yeast: two distinct GPCR systems. EMBO Rep. 2001, 2: 574-579. 10.1093/embo-reports/kve132.
Article
CAS
Google Scholar
Schoneberg T, Schulz A, Gudermann T: The structural basis of G-protein-coupled receptor function and dysfunction in human diseases. Rev Physiol Biochem Pharmacol. 2002, 144: 143-227.
CAS
Google Scholar
Altenbach C, Yang K, Farrens DL, Farahbakhsh ZT, Khorana HG, Hubbell WL: Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study. Biochemistry. 1996, 35: 12470-12478. 10.1021/bi960849l.
Article
CAS
Google Scholar
Ghanouni P, Steenhuis JJ, Farrens DL, Kobilka BK: Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor. Proc Natl Acad Sci USA. 2001, 98: 5997-6002. 10.1073/pnas.101126198.
Article
CAS
Google Scholar
Jensen AD, Guarnieri F, Rasmussen SG, Asmar F, Ballesteros JA, Gether U: Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling. J Biol Chem. 2001, 276: 9279-9290. 10.1074/jbc.M004871200.
Article
CAS
Google Scholar
Rasmussen SG, Jensen AD, Liapakis G, Ghanouni P, Javitch JA, Gether U: Mutation of a highly conserved aspartic acid in the beta2 adrenergic receptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6. Mol Pharmacol. 1999, 56: 175-184.
CAS
Google Scholar
Ward SD, Hamdan FF, Bloodworth LM, Siddiqui NA, Li JH, Wess J: Use of an in situ disulfide cross-linking strategy to study the dynamic properties of the cytoplasmic end of transmembrane domain VI of the M3 muscarinic acetylcholine receptor. Biochemistry. 2006, 45: 676-685. 10.1021/bi051503q.
Article
CAS
Google Scholar
Granier S, Kim S, Shafer AM, Ratnala VR, Fung JJ, Zare RN, Kobilka B: Structure and conformational changes in the C-terminal domain of the beta2-adrenoceptor: insights from fluorescence resonance energy transfer studies. J Biol Chem. 2007, 282: 13895-13905. 10.1074/jbc.M611904200.
Article
CAS
Google Scholar
Li JH, Han SJ, Hamdan FF, Kim SK, Jacobson KA, Bloodworth LM, Zhang X, Wess J: Distinct Structural Changes in a G Protein-coupled Receptor Caused by Different Classes of Agonist Ligands. J Biol Chem. 2007, 282: 26284-26293. 10.1074/jbc.M704875200.
Article
CAS
Google Scholar
Vilardaga JP, Steinmeyer R, Harms GS, Lohse MJ: Molecular basis of inverse agonism in a G protein-coupled receptor. Nat Chem Biol. 2005, 1: 25-28. 10.1038/nchembio705.
Article
CAS
Google Scholar
Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL: Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand. Proc Natl Acad Sci USA. 2007, 104: 5163-5168. 10.1073/pnas.0700293104.
Article
Google Scholar
Coward P, Wada HG, Falk MS, Chan SD, Meng F, Akil H, Conklin BR: Controlling signaling with a specifically designed Gi-coupled receptor. Proc Natl Acad Sci USA. 1998, 95: 352-357. 10.1073/pnas.95.1.352.
Article
CAS
Google Scholar
Schulein R, Rutz C, Rosenthal W: Membrane targeting and determination of transmembrane topology of the human vasopressin V2 receptor. J Biol Chem. 1996, 271: 28844-28852. 10.1074/jbc.271.46.28844.
Article
CAS
Google Scholar
Nakano Y, Nystedt S, Shivdasani AA, Strutt H, Thomas C, Ingham PW: Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila. Mech Dev. 2004, 121: 507-518. 10.1016/j.mod.2004.04.015.
Article
CAS
Google Scholar
Zeng FY, McLean AJ, Milligan G, Lerner M, Chalmers DT, Behan DP: Ligand specific up-regulation of a Renilla reniformis luciferase-tagged, structurally unstable muscarinic M3 chimeric G protein-coupled receptor. Mol Pharmacol. 2003, 64: 1474-1484. 10.1124/mol.64.6.1474.
Article
CAS
Google Scholar
Gales C, Rebois RV, Hogue M, Trieu P, Breit A, Hebert TE, Bouvier M: Real-time monitoring of receptor and G-protein interactions in living cells. Nat Methods. 2005, 2: 177-184. 10.1038/nmeth743.
Article
CAS
Google Scholar
Vilardaga JP, Bunemann M, Krasel C, Castro M, Lohse MJ: Measurement of the millisecond activation switch of G protein-coupled receptors in living cells. Nat Biotechnol. 2003, 21: 807-812. 10.1038/nbt838.
Article
CAS
Google Scholar
Angers S, Salahpour A, Joly E, Hilairet S, Chelsky D, Dennis M, Bouvier M: Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proc Natl Acad Sci USA. 2000, 97: 3684-3689. 10.1073/pnas.060590697.
CAS
Google Scholar
Moreau CJ, Dupuis JP, Revilloud J, Arumugam K, Vivaudou M: Coupling ion channels to receptors for biomolecule sensing. Nat Nanotechnol. 2008, 3: 620-625. 10.1038/nnano.2008.242.
Article
CAS
Google Scholar
Maggio R, Barbier P, Fornai F, Corsini GU: Functional role of the third cytoplasmic loop in muscarinic receptor dimerization. J Biol Chem. 1996, 271: 31055-31060. 10.1074/jbc.271.49.31055.
Article
CAS
Google Scholar
Schoneberg T, Liu J, Wess J: Plasma membrane localization and functional rescue of truncated forms of a G protein-coupled receptor. J Biol Chem. 1995, 270: 18000-18006. 10.1074/jbc.270.30.18000.
Article
CAS
Google Scholar
Zeng FY, Wess J: Identification and molecular characterization of m3 muscarinic receptor dimers. J Biol Chem. 1999, 274: 19487-19497. 10.1074/jbc.274.27.19487.
Article
CAS
Google Scholar
Wess J, Blin N, Yun J, Schoneberg T, Liu J: G protein-coupled receptors: structural basis of receptor assemply and G protein recognition. Alfred Benzon Symposium 39: Structure and Function of 7TM Receptors. Edited by: Schwartz TW, Hjorth SA, Sandholm Kastrup J. 1996, Copenhagen: Blackwell Munksgaard, 43-56.
Google Scholar
Wang XC, Yang J, Huang W, He L, Yu JT, Lin QS, Li W, Zhou HM: Effects of removal of the N-terminal amino acid residues on the activity and conformation of firefly luciferase. Int J Biochem Cell Biol. 2002, 34: 983-991. 10.1016/S1357-2725(02)00019-5.
Article
CAS
Google Scholar
Conti E, Franks NP, Brick P: Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes. Structure. 1996, 4: 287-298. 10.1016/S0969-2126(96)00033-0.
Article
CAS
Google Scholar
Lysikova M, Havlas Z, Tucek S: Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists. Neurochem Res. 2001, 26: 383-394. 10.1023/A:1010951131496.
Article
CAS
Google Scholar
Spalding TA, Burstein ES: Constitutive activity of muscarinic acetylcholine receptors. J Recept Signal Transduct Res. 2006, 26: 61-85. 10.1080/10799890600567349.
Article
CAS
Google Scholar
Berridge MJ: Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol. Biochem J. 1983, 212: 849-858.
Article
CAS
Google Scholar
van Leeuwen W, Hagendoorn MJM, Ruttink T, van Poecke R, Plas van der LHW, Krol van der AR: The use of the luciferase reporter system for in planta gene expression studies. Plant Mol Biol Rep. 2000, 18: 143a-143t. 10.1007/BF02824024.
Article
Google Scholar
Schoneberg T, Sandig V, Wess J, Gudermann T, Schultz G: Reconstitution of mutant V2 vasopressin receptors by adenovirus-mediated gene transfer. Molecular basis and clinical implication. J Clin Invest. 1997, 100: 1547-1556. 10.1172/JCI119678.
Article
CAS
Google Scholar