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Fig. 3 | BMC Biotechnology

Fig. 3

From: Characterization of metabolic responses, genetic variations, and microsatellite instability in ammonia-stressed CHO cells grown in fed-batch cultures

Fig. 3

KEGG enrichment results from over representation analysis of ammonia-sensitive genes linked to genomic instability. a Network plot of most significant enriched KEGG pathways. Enrichment scores (i.e., adjusted p values) and gene counts (the number of genes enriched in a KEGG term) are depicted by dot color and size. b Comparison of enrichment results of KEGG pathways for genes identified with significant variants in the 10 mM Ammonia-stressed culture (111 genes), in the 30 mM culture (102 genes), and in the union of 10 mM and 30 mM cultures (148 genes). Enrichment scores (i.e., adjusted p values) and gene ratios (the percentage of total genes in the given KEGG term) are depicted by dot color and size. The plots are made with clusterProfiler

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BMC Biotechnology

ISSN: 1472-6750

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