Alix-Panabieres C, Riethdorf S, Pantel K: Circulating tumor cells and bone marrow micrometastasis. Clin Cancer Res. 2008, 14: 5013-21. 10.1158/1078-0432.CCR-07-5125.
Article
CAS
Google Scholar
Weitz J, Koch M, Debus J, Hohler T, Galle PR, Buchler MW: Colorectal cancer. Lancet. 2005, 365: 153-65. 10.1016/S0140-6736(05)17706-X.
Article
Google Scholar
Rahbari NN, Aigner M, Thorlund K, Mollberg N, Motschall E, Jensen K, Diener MK, Büchler MW, Koch M, Weitz J: Meta-Analysis Shows that Detection of Circulating Tumor Cells Indicates Poor Prognosis in Patients with Colorectal Cancer. Gastroenterology. 2010, 138 (5): 1714-26. 10.1053/j.gastro.2010.01.008.
Article
Google Scholar
Koch M, Beckhove P, Op den Winkel J, Autenrieth D, Wagner P, Nummer D, Specht S, Antolovic D, Galindo L, Schmitz-Winnenthal FH, Schirrmacher V, Buchler MW, et al: Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ. Ann Surg. 2006, 244: 986-92. 10.1097/01.sla.0000247058.43243.7b. discussion 92-3
Article
Google Scholar
Koch M, Kienle P, Kastrati D, Antolovic D, Schmidt J, Herfarth C, von Knebel Doeberitz M, Weitz J: Prognostic impact of hematogenous tumor cell dissemination in patients with stage II colorectal cancer. Int J Cancer. 2006, 118: 3072-7. 10.1002/ijc.21784.
Article
CAS
Google Scholar
Weitz J, Kienle P, Magener A, Willeke F, Lehnert T, Herfarth C, von Knebel Doeberitz M: [Detection of isolated disseminated tumor cells of colorectal carcinomas in lymph nodes]. Langenbecks Arch Chir Suppl Kongressbd. 1998, 115: 319-22.
CAS
Google Scholar
Weitz J, Kienle P, Lacroix J, Willeke F, Benner A, Lehnert T, Herfarth C, von Knebel Doeberitz M: Dissemination of tumor cells in patients undergoing surgery for colorectal cancer. Clin Cancer Res. 1998, 4: 343-8.
CAS
Google Scholar
Kienle P, Koch M: Minimal residual disease in gastrointestinal cancer. Semin Surg Oncol. 2001, 20: 282-93. 10.1002/ssu.1046.
Article
CAS
Google Scholar
Balzar M, Winter MJ, de Boer CJ, Litvinov SV: The biology of the 17-1A antigen (Ep-CAM. J Mol Med. 1999, 77: 699-712. 10.1007/s001099900038.
Article
CAS
Google Scholar
Balzar M, Briaire-de Bruijn IH, Rees-Bakker HA, Prins FA, Helfrich W, de Leij L, Riethmuller G, Alberti S, Warnaar SO, Fleuren GJ, Litvinov SV: Epidermal growth factor-like repeats mediate lateral and reciprocal interactions of Ep-CAM molecules in homophilic adhesions. Mol Cell Biol. 2001, 21: 2570-80. 10.1128/MCB.21.7.2570-2580.2001.
Article
CAS
Google Scholar
Latza U, Niedobitek G, Schwarting R, Nekarda H, Stein H: Ber-EP4: new monoclonal antibody which distinguishes epithelia from mesothelial. J Clin Pathol. 1990, 43: 213-9. 10.1136/jcp.43.3.213.
Article
CAS
Google Scholar
Perez MS, Walker LE: Isolation and characterization of a cDNA encoding the KS1/4 epithelial carcinoma marker. J Immunol. 1989, 142: 3662-7.
CAS
Google Scholar
Chambers AF, Groom AC, MacDonald IC: Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer. 2002, 2: 563-72. 10.1038/nrc865.
Article
CAS
Google Scholar
Fidler IJ: The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer. 2003, 3: 453-8. 10.1038/nrc1098.
Article
CAS
Google Scholar
Denis MG, Lipart C, Leborgne J, LeHur PA, Galmiche JP, Denis M, Ruud E, Truchaud A, Lustenberger P: Detection of disseminated tumor cells in peripheral blood of colorectal cancer patients. Int J Cancer. 1997, 74: 540-4. 10.1002/(SICI)1097-0215(19971021)74:5<540::AID-IJC11>3.0.CO;2-A.
Article
CAS
Google Scholar
Guo J, Xiao B, Zhang X, Jin Z, Chen J, Qin L, Mao X, Shen G, Chen H, Liu Z: Combined use of positive and negative immunomagnetic isolation followed by real-time RT-PCR for detection of the circulating tumor cells in patients with colorectal cancers. J Mol Med. 2004, 82: 768-74. 10.1007/s00109-004-0590-8.
Article
CAS
Google Scholar
de Cremoux P, Extra JM, Denis MG, Pierga JY, Bourstyn E, Nos C, Clough KB, Boudou E, Martin EC, Muller A, Pouillart P, Magdelenat H: Detection of MUC1-expressing mammary carcinoma cells in the peripheral blood of breast cancer patients by real-time polymerase chain reaction. Clin Cancer Res. 2000, 6: 3117-22.
CAS
Google Scholar
Jung R, Kruger W, Hosch S, Holweg M, Kroger N, Gutensohn K, Wagener C, Neumaier M, Zander AR: Specificity of reverse transcriptase polymerase chain reaction assays designed for the detection of circulating cancer cells is influenced by cytokines in vivo and in vitro. Br J Cancer. 1998, 78: 1194-8.
Article
CAS
Google Scholar
Jung R, Petersen K, Kruger W, Wolf M, Wagener C, Zander A, Neumaier M: Detection of micrometastasis by cytokeratin 20 RT-PCR is limited due to stable background transcription in granulocytes. Br J Cancer. 1999, 81: 870-3. 10.1038/sj.bjc.6690778.
Article
CAS
Google Scholar
Lopez-Guerrero JA, Bolufer-Gilabert P, Sanz-Alonso M, Barragan-Gonzalez E, Palau-Perez J, De la Rubia-Comos J, Sempere-Talens A, Bonanad-Boix S: Minimal illegitimate levels of cytokeratin K19 expression in mononucleated blood cells detected by a reverse transcription PCR method (RT-PCR). Clin Chim Acta. 1997, 263: 105-16. 10.1016/S0009-8981(97)00054-5.
Article
CAS
Google Scholar
Traweek ST, Liu J, Battifora H: Keratin gene expression in non-epithelial tissues. Detection with polymerase chain reaction. Am J Pathol. 1993, 142: 1111-8.
CAS
Google Scholar
Vlems F, Soong R, Diepstra H, Punt C, Wobbes T, Tabiti K, van Muijen G: Effect of blood sample handling and reverse transcriptase-polymerase chain reaction assay sensitivity on detection of CK20 expression in healthy donor blood. Diagn Mol Pathol. 2002, 11: 90-7. 10.1097/00019606-200206000-00005.
Article
Google Scholar
Cohen SJ, Punt CJ, Iannotti N, Saidman BH, Sabbath KD, Gabrail NY, Picus J, Morse M, Mitchell E, Miller MC, Doyle GV, Tissing H, Terstappen LW, Meropol NJ: Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer. J Clin Oncol. 2008, 26 (19): 3213-21. 10.1200/JCO.2007.15.8923.
Article
Google Scholar
Paterlini-Brechot P, Benali NL: Circulating tumor cells (CTC) detection: clinical impact and future directions. Cancer Lett. 2007, 253: 180-204. 10.1016/j.canlet.2006.12.014.
Article
CAS
Google Scholar
Fehm T, Sagalowsky A, Clifford E, Beitsch P, Saboorian H, Euhus D, Meng S, Morrison L, Tucker T, Lane N, Ghadimi BM, Heselmeyer-Haddad K, Ried T, Rao C, Uhr J: Cytogenetic evidence that circulating epithelial cells in patients with carcinoma are malignant. Clin Cancer Res. 2002, 8: 2073-2084.
CAS
Google Scholar
Willipinski-Stapelfeldt B, Riethdorf S, Assmann V, Woelfle U, Rau T, Sauter G, Heukeshoven J, Pantel K: Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells. Clin Cancer Res. 2005, 11: 8006-8014. 10.1158/1078-0432.CCR-05-0632.
Article
CAS
Google Scholar
Wong SC, Chan CM, Ma BB, Hui EP, Ng SS, Lai PB, Cheung MT, Lo ES, Chan AK, Lam MY, Au TC, Chan AT: Clinical significance of cytokeratin 20-positive circulating tumor cells detected by a refined immunomagnetic enrichment assay in colorectal cancer patients. Clin Cancer Res. 2009, 15 (3): 1005-12. 10.1158/1078-0432.CCR-08-1515.
Article
CAS
Google Scholar
Wittekind Ch, Meyer HJ, Bootz F: TNM Klassifikation maligner Tumoren. 6. Auflage. 2003, Springer Verlag
Google Scholar