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Fig. 5 | BMC Biotechnology

Fig. 5

From: Staphopain mediated virulence and antibiotic resistance alteration in co-infection of Staphylococcus aureus and Pseudomonas aeruginosa: an animal model

Fig. 5

Staphopain A treatment influence on antibiotic resistance. a: The combination of vancomycin and Staphopain A, doripenem, and Staphopain A in co-culture group. The MIC of vancomycin and doripenem is shown in combination with Staphopain A. b: The expression level of kpc, oprD, and mexA-mexB-oprM in co- and mono-infection groups after treatment with Staphopain A. c: The viable colony counts of S. aureus and P.aeruginosa isolates after combination therapy in the co-culture model. The data were presented as Mean + SEM. * p-value < 0.05; ** p-value < 0.01; *** p-value < 0.001; **** p-value < 0.0001

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BMC Biotechnology

ISSN: 1472-6750

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