Fig. 3
The sigB expression levels in treated and control groups in animal models. a: The expression level of sigB in S. aureus in co- and mono-infection groups. C1, C5, and C10 indicate the control groups in days 1, 5, and 10 after infection. T1, T5, and T10 indicate the treated groups in days 1, 5, and 10 after infection. b and c: S. aureus isolates were recovered in BHI agar (b) and Columbia agar supplemented with sheep blood (c). A heterogeneous population of the slow-growing, tiny isolates, and normal isolates were indicated on the plates. d and e: The pigment inactivation in P. aeruginosa isolates. The dark blue arrow shows pigment production in the treated co-infection group. The black and green arrows show colonies without pigment in co- and mono-infection control groups. Each data set was analyzed using the two-way ANOVA, and the Holm-Sidak method for multiple comparisons. The data were presented as Mean + SEM. * p-value < 0.05; ** p-value < 0.01; *** p-value < 0.001; **** p-value < 0.0001