Table 2 Accuracy and precision of the LC-MS/MS method for the determination of CML and CEL in human plasma
Theoretical concentration (μmol/L) | Measured concentration (μmol/L) | RE (%) | Intra-batch RSD (%) | Inter-batch RSD (%) | |
|---|---|---|---|---|---|
CML | 0.15 | 0.149 ± 0.013 | −0.9 | 6.6 | 4.1 |
0.45 | 0.440 ± 0.047 | −2.3 | 6.3 | 5.1 | |
1.00 | 0.964 ± 0.110 | −3.6 | 3.6 | 6.5 | |
CEL | 0.15 | 0.146 ± 0.013 | −2.5 | 9.0 | 4.2 |
0.45 | 0.465 ± 0.030 | 3.3 | 4.3 | 5.6 | |
1.00 | 0.961 ± 0.125 | −3.9 | 2.9 | 6.5 |