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Fig. 2 | BMC Biotechnology

Fig. 2

From: Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice

Fig. 2

Polyphyllin B inhibited lung and peripheral blood inflammation in CSE and LPS-induced mice. A HE staining was applied to observe the pathology of lung tissue. B The levels of IgA and IgG in BALF were analyzed by ELISA. C RT-qPCR was applied to detect the expression of pIgR and FcRn in mouse lung tissues. D The levels of IFN-γ, TNF-α and IL-6 in BALF and lung tissue homogenate were analyzed by ELISA. E ELISA was applied to detect the LPS, TNF-α and IL-6 levels in peripheral blood. F The expressions of TLR2, TLR4 and p65 in lung tissue were detected by western blot. Full-length blots/gels are presented in Supplementary Fig. 2A. *P < 0.05 vs Control, #P < 0.05 vs C + L. N = 6 mice/group

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BMC Biotechnology

ISSN: 1472-6750

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