Table 3 Predicted half-life of the peptide. The HLP half-life prediction tool indicated a short half-life of the peptide sequence (around 1 s) with normal stability
Peptide Sequence | Mutation Position | Half-life (sec) | Stability | HPLC parameter | Hydrophobicity (KJ/mol) | pKa | pKb | Residue volume | Molecular weight | Isoelectric Point |
|---|---|---|---|---|---|---|---|---|---|---|
AAEKEFIKYPYPTPLQYQQ LATRLKVEKKLVRRW | No | 0.945 | Normal | 1.42 | 10.4 | 21.8 | 93.98 | 1481.5 | 1195.51 | 6.138 |