Fig. 6

Susceptibility of S. aureus and E. coli to the peptide. A S. aureus representative plate images of inhibition zones generated by clindamycin [C], erythromycin [E], and peptide [P] disks following 24 h inverted incubation at 37 °C. B Average inhibition zone diameters (cm) caused by the antibiotics and the IC50 concentration of the peptide on S. aureus cells. Inhibition zones were not observed in peptide treated disks, contrasting with statistically larger [C] and [E] zones. C E. coli representative plate images of inhibition zones generated by imipenem [I], tetracycline [T], and IC50 peptide [P] disks, following 24 h incubation at 37 °C. D Average diameter inhibition zones (cm) from antibiotic exposure and IC50 concentration of the peptide on E. coli spread plates. Inhibition zones were not observed around peptide disks, contrasting with antibiotic impregnated disks, where [I] and [T] showed significant inhibition zones