Induction of antimicrobial, antioxidant metabolites production by co-cultivation of two red-sea-sponge-associated Aspergillus sp. CO2 and Bacillus sp. COBZ21

Table 8 Pharmacokinetics parameters of Ba-Asp

Pharmacokinetics Parameters	C1
GI (HIA) absorption	Low
BBB permeant	No
P-gp substrate	Yes
CYP1A2 inhibitor CYP2C19 inhibitor CYP2C9 inhibitor	No
	No
	No
CYP2D6 inhibitor	No
CYP3A4 inhibitor	No
Log K_p (skin permeation: cm/s)	-2.53 cm/s

GI (HIA) = Human gastrointestinal absorption, BBB = Blood-brain barrier permeation P-gp = Permeability glycoprotein, Log K_p = The skin permeability coefficient

ISSN: 1472-6750