Table 2 Helper T-Lymphocyte epitopes and their scores anticipated using the IEDB MHC class II server
Protein | Allele | Start | End | Length | Method | Peptide | Percentile rank |
|---|---|---|---|---|---|---|---|
APO | HLA-DRB4*01:01 | 346 | 360 | 15 | Consensus (comb.lib./smm/nn) | PLICYEGTSKAAYSN | 64 |
HLA-DRB1*03:01 | 367 | 381 | 15 | Consensus (smm/nn/sturniolo) | IVMSNNAWFSPSIEP | 19 | |
HLA-DRB1*03:01 | 267 | 281 | 15 | Consensus (smm/nn/sturniolo) | ILIGTLRTQGYNLYN | 35 | |
LeoA | HLA-DRB1*07:01 | 34 | 48 | 15 | Consensus (comb.lib./smm/nn) | QKKIKENGGKLTIIE | 52 |
IceA1 (AAL59391.1) | HLA-DRB1*01:01 | 33 | 47 | 15 | Consensus (comb.lib./smm/nn) | YQGLQLGNGGSWRNN | 53 |
HLA-DRB1*07:01 | 55 | 69 | 15 | Consensus (comb.lib./smm/nn) | EFDKGQTPGNSIDRI | 48 | |
HLA-DRB1*04:01 | 121 | 135 | 15 | Consensus (smm/nn/sturniolo) | DLRVSDSNTQTFDDF | 14 | |
IceA2 (AAG49536.1) | HLA-DRB5*01:01 | 253 | 267 | 15 | Consensus (smm/nn/sturniolo) | AAYTPFTPKGKTGLP | 4.3 |
HLA-DRB5*01:01 | 60 | 74 | 15 | Consensus (smm/nn/sturniolo) | AGTGIVGRAFKKAVN | 21 | |
HLA-DRB4*01:01 | 144 | 158 | 15 | Consensus (comb.lib./smm/nn) | MRLKIEELKLSQNID | 7.2 |