Table 1 Substances and technological parameters of diverse formulation
Formulation | VAN (mg) | LYS (mg) | PLGA (mg) | DCMa (ml) | Chlb (ml) | PVA (ml) | Size (nm) | PDI | ZP (mV) | EE (%) | DL (%) | LCEc (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
F1 | 6 | - | 30 | 20 | - | 20 (1%) | 674.4 ± 23 | 0.386 ± 0.024 | -17.2 ± 2.3 | 91.35 ± 6.2 | 14.25 ± 2.5 | - |
F2 | 6 | - | 30 | - | 15 | 20 (1%) | 494.5 ± 27 | 0.292 ± 0.026 | -18.7 ± 1.8 | 92.46 ± 3.4 | 15.27 ± 2.7 | - |
F3 | 12 | - | 60 | - | 15 | 2 (2%) | 388.6 ± 38 | 0.279 ± 0.015 | -21.2 ± 1.4 | 94.35 ± 2.5 | 16.23 ± 1.3 | - |
F4 | 24 | 3 | 120 | - | 15 | 20 (2%) | 320.5 ± 35 | 0.270 ± 0.012 | -19.5 ± 1.3 | 94.62 ± 2.6 | 16.75 ± 2.5 | 37 |