Fig. 9
From: Expression and characterization of recombinant IL-1Ra in Aspergillus oryzae as a system
SPR sensorgrams of (A) Asp. IL-1Ra and (B) Anakinra (Kineret). The kinetic models show that the calculated binding affinity of Asp. IL-1Ra and Anakinra. The colored lines show the measured curves for the different concentrations, and the black lines show the fit curves. For Asp. IL-1Ra, 500 nM, 100 nM, 20 nM, and 4 nM were represented by purple, blue, green, and red lines, respectively. For Anakinra, 5 nM, 1 nM, 0.2 nM, and 0.04 nM were represented by purple, blue, green, and red lines, respectively. RU: response unit