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Fig. 5 | BMC Biotechnology

Fig. 5

From: A fully human connective tissue growth factor blocking monoclonal antibody ameliorates experimental rheumatoid arthritis through inhibiting angiogenesis

Fig. 5

Effect of IgG mut-B2 on angiogenesis. (A) Cell migration assay used to assess angiogenesis in vitro. Lower right panel: numbers of HUVEC per field. (Original magnifcation, ×200) (B) Tube formation assay used to assess angiogenesis in vitro. Lower right panel: numbers of intersection nodes. (Original magnifcation, ×100) (C) Chorioallantoic membrane (CAM) assay used to assess angiogenesis in vivo. Lower right panel: ratio of vascular area to CAM area

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