Table 2 Resolution of the NOMe-Seq analysis
Sequence motif | Genome size (hg19) | Number of motifs in hg19 | Analytical resolution (bp) | Number of motifs with ten or more read coverage | |||||
|---|---|---|---|---|---|---|---|---|---|
Control (No MTase) | NOMe-Seq (CCMT) | NOMe-Seq (GCMT) | |||||||
CG | 3,137,161,264 | 57,400,172 | 55 | 37,593,561 | 65.5% | 35,968,639 | 62.7% | 32,224,228 | 56.1% |
HCG | 43,525,732 | 72 | 28,851,898 | 66.3% | 27,661,596 | 63.6% | 24,764,078 | 56.9% | |
GC | 247,517,634 | 13 | 174,727,329 | 70.6% | 169,559,103 | 68.5% | 151,895,283 | 61.4% | |
GCH | 233,643,193 | 13 | 165,985,668 | 71.0% | 161,252,061 | 69.0% | 144,435,133 | 61.8% | |
CC | 302,651,847 | 10 | 215,834,149 | 71.3% | 208,676,370 | 68.9% | 187,023,053 | 61.8% | |