Fig. 5

NOMe-Seq of fixed yeast nuclei. A Comparison of methylation levels between CCMT- and GCMT-treated nuclei. Bin size is 10 bp. B Genome browser screenshot showing annotated yeast genes (Track 1), DNA methylation levels at the GC sites (Track 2, NOMe-Seq using GCMT) and CC sites (Track 3, NOMe-Seq using CCMT), read coverage of ATAC-Seq (Track 4, SRR12926697) [36], and MNase-Seq (Track 5, SRR6729489) [37]. C–E Aggregation plots around the initiation codons of yeast genes. DNA methylation signals at CC (C) and GC (D) sites, as well as read coverage of MNase-Seq (E) (SRR6729489), are shown