Oil–water partition coefficient preparation and detection in the dihydroartemisinin self-emulsifying drug delivery system

Table 6 The results of the apparent oil–water partition coefficient of dihydroartemisinin crude drug

The solvent	The crude drug		SEDDS
The solvent	P_app	logP_app	P_app	logP_app
Distilled water	− 64.8182	− 1.8117	29.0999	1.4639
Hydrochloric acid solution pH 1.2	− 12.4463	− 1.0950	22.6545	1.3552
Phosphate buffer pH 4.5	− 1.3144	− 0.1187	43.9862	1.6433
Phosphate buffer pH 6.8	− 1.1964	− 0.0779	24.8717	1.3957
Phosphate buffer pH 7.4	− 47.8224	− 1.6796	20.6708	1.3154

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