Table 1 The solubility of dihydroartemisinin in different oil phases, emulsifiers, and co-emulsifiers
Oil phase | Solubility | Surfactant | Solubility | Co-surfactant | Solubility |
|---|---|---|---|---|---|
Medium chain triglyceride | 2.578 | Tween-20 | 15.702 | Glycerin | 31.520 |
Glyceryl monooleate | 8.478 | Tween-40 | 9.379 | Polyethylene glycol | 8.170 |
Soybean oil | 5.130 | Tween-60 | 6.571 | Diethylene glycol ether | 17.083 |
Corn oil | 1.829 | Tween-80 | 8.665 | Diethylene glycol monoethyl ether | 46.679 |
Olive oil | 2.259 | Span-80 | 10.966 | 1,2-Propanediol | 3.637 |
Castor oil | 2.468 | Isopropyl myristate | 2.093 | Isopropanol | 9.364 |
Ethyl oleate | 5.525 | Triethanolamine | 4.740 | ||
Oleic acid polyethylene glycol glyceride | 12.113 | Span-85 | 1.182 | ||
Oleic acid | 1.954 | Polyethylene glycol monooleate | 11.326 | ||
Castor oil polyoxyethylene ether | 12.573 | ||||
Isopropyl palmitate | 0.890 | ||||
Oleoyl polyoxyethylene glyceride | 8.256 | ||||
Polyethylene glycol-7-stearate | 3.324 | ||||
Polyoxyethylene hydrogenated castor oil | 6.518 | ||||
Caprylic acid capric acid polyethylene glycol glyceride | 32.558 |