|
rec-eCG
|
cAMP responses
|
|---|
|
Basala (nM/104 cells)
|
EC50b (ng/mL)
|
Rmaxc (nM/104 cells)
|
|---|
|
rec-eCGβ/α-wt
|
0.4 ± 0.1
|
27.1 (1.0-fold) (20.2 to 40.8) d
|
16.5 ± 0.5 (1.0-fold)
|
|
rec-eCGβ/αΔ56
|
0.4 ± 0.1
|
111.5 (4.1-fold) (94.8 to 135.2)
|
5.5 ± 0.2 (0.33-fold)
|
|
rec-eCGβ-D/α
|
0.3 ± 0.1
|
63.1 (2.3-fold) (51.3 to 81.9)
|
14.2 ± 0.4 (0.86-fold)
|
|
rec-eCGβ-D/αΔ56
|
0.4 ± 0.1
|
94.9 (3.5-fold) (69.8 to 147.8)
|
5.4 ± 0.3 (0.32-fold)
|
- Values are the means ± SEM of triplicate experiments. EC50 values were determined from the concentration–response curves from in vitro bioassays. The cAMP responses of the basal and Rmax in rec-eCGβ/α-wild type were shown as onefold
- aBasal cAMP level average without agonist treatment
- bGeometric mean (95% confidence limit)
- cRmax average cAMP level/104 cells
- d95% Confidence intervals
