|
rec-eCG
|
cAMP responses
|
|---|
|
Basala (nM/104 cells)
|
EC50b (ng/mL)
|
Rmaxc (nM/104 cells)
|
|---|
|
rec-eCGβ/α-wt
|
0.4 ± 0.1
|
4.6 (1.0-fold) (3.6 to 6.3)d
|
23.1 ± 0.5 (1.0-fold)
|
|
rec-eCGβ/αΔ56
|
0.3 ± 0.1
|
17.63 (3.8-fold) (13.9 to 24.1)
|
11.6 ± 0.3 (0.50-fold)
|
|
rec-eCGβ-D/α
|
0.3 ± 0.1
|
24.5 (5.3-fold) (20.9 to 29.6)
|
20.3 ± 0.4 (0.88-fold)
|
|
rec-eCGβ-D/αΔ56
|
0.2 ± 0.1
|
334.2 (72.7-fold) (282.4 to 409.1)
|
10.3 ± 0.4 (0.45-fold)
|
- Values are the means ± SEM of triplicate experiments. EC50 values were determined from the concentration–response curves from in vitro bioassays. The cAMP responses of the basal and Rmax in rec-eCGβ/α-wild type were shown as onefold
- aBasal cAMP level average without agonist treatment
- bGeometric mean (95% confidence limit)
- cRmax average cAMP level/104 cells
- d95% Confidence intervals
