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Table 5 Summary of recent reports of fibrinolytic enzyme expression in the literature

From: An effective combination of codon optimization, gene dosage, and process optimization for high-level production of fibrinolytic enzyme in Komagataella phaffii (Pichia pastoris)

Wild-type strain

Host (strains/plasmids)

Fibase activity

References

Paenibacillus polymyxa EJS-3

E. coli BL21 (DE3)/pET-DsbA

228.0 U/ml

[8] (Lv et al. 2015)

Bacillus amyloliquefaciens

B. subtilis WB600/pSUGV4

200.0 U/ml

[46] (Xiao et al. 2004)

Bacillus pumilus BS15

B. subtilis WB600 /pHY300PLK

408.2 U/ml

[47] (Yao et al. 2018)

Bacillus pumilus BS15

none

242.5 U/ml

[47] (Yao et al. 2018)

Xanthomonas oryzae IND3

none

2294 ± 12.8 U/g

[48] (Vijayaraghavan et al. 2019)

Serratia KG-2-1

none

250.4 U/ml

[9] (Taneja et al. 2017)

Serratia rubidaea

none

394.9 U/ml

[49] (Anusree et al. 2020)

Bacillus sp. IND12

none

4143 U/g

[50] (Vijayaraghavan et al. 2017)

Cordyceps militaris

none

120.0 U/ml

[51] (Liu et al. 2017)

B. subtilis D21

none

279 U/ml

This research

B. subtilis D21

K. phaffii GS115 /pPIC9K

7930/12690 U/ml

This research