| |
L.p-control
|
L.p-pcDNA3.1
|
L.p-PAL/PiLE/FLaA
|
|---|
|
TNF-α
|
12 h
|
28.464 ± 3.656
|
30.544 ± 3.160
|
66.426 ± 6.966***
|
|
24 h
|
63.061 ± 6.975
|
66.022 ± 7.707
|
142.812 ± 18.872***
|
|
48 h
|
74.966 ± 8.033
|
79.856 ± 8.523
|
155.792 ± 16.642***
|
|
72 h
|
71.350 ± 7.257
|
78.119 ± 8.014
|
176.366 ± 19.816***
|
|
IFNγ
|
12 h
|
17.882 ± 2.151
|
18.063 ± 1.958
|
168.855 ± 17.771***
|
|
24 h
|
42.829 ± 6.708
|
41.573 ± 6.185
|
259.489 ± 31.379***
|
|
48 h
|
27.588 ± 4.677
|
28.726 ± 5.612
|
361.732 ± 39.412***
|
|
72 h
|
32.878 ± 3.567
|
35.138 ± 4.788
|
442.975 ± 51.127***
|
|
IL-10
|
12 h
|
35.905 ± 5.921
|
38.285 ± 6.257
|
638.272 ± 72.853***
|
|
24 h
|
26.358 ± 2.762
|
25.189 ± 3.560
|
597.381 ± 70.460***
|
|
48 h
|
18.722 ± 2.776
|
18.359 ± 3.338
|
580.414 ± 71.515***
|
|
72 h
|
23.453 ± 4.065
|
22.517 ± 4.267
|
464.455 ± 47.797***
|
|
12 h
|
7.545 ± 0.848
|
7.866 ± 0.832
|
166.512 ± 19.016***
|
|
24 h
|
9.129 ± 1.099
|
9.616 ± 1.083
|
153.189 ± 16.667***
|
|
IL-4
|
48 h
|
16.399 ± 2.269
|
18.371 ± 2.041
|
180.543 ± 20.530***
|
|
72 h
|
19.566 ± 2.546
|
21.151 ± 3.770
|
182.311 ± 23.732***
|
|
12 h
|
32.346 ± 3.307
|
31.066 ± 3.123
|
187.781 ± 24.391***
|
|
24 h
|
25.581 ± 2.879
|
24.311 ± 2.506
|
263.204 ± 38.746***
|
|
IL-12
|
48 h
|
21.841 ± 2.484
|
22.015 ± 2.566
|
360.088 ± 60.515***
|
|
72 h
|
27.231 ± 3.618
|
27.220 ± 3.528
|
439.624 ± 50.110***
|
- ***, p < 0.001 versus the L.p-pcDNA3.1 group
