Parameter | Cultivation conditions | ||||
---|---|---|---|---|---|
Shake-flask cultivation | Bioreactor cultivation | ||||
Batch (20 g/L) | Intermittent feeding (glucose+beef) | Intermittent feeding (glucose) | Batch (20 g/L) | Glucose feeding | |
Xmax (g/L) | 4.780 ± 0.13 | 12.25 ± 0.45 | 9.030 ± 0.84 | 6.460 ± 0.04 | 6.21 ± 0.05 |
Pmax (g/L) | 1.580 ± 0.03 | 1.855 ± 0.1 | 2.480 ± 0.04 | 1.710 ± 0.01 | 2.72 ± 0.01 |
Qxa (g/L/h) | 0.099 | 0.080 | 0.085 | 0.111 | 0.103b |
Qpa (g/L/h) | 0.021 | 0.022 | 0.023 | 0.038 | 0.045b |
Qsa (g/L/h) | −0.41 | −0.31 | −0.220 | −0.443 | −0.448 |
Yx/s (g/g) | 0.280 | 0.260 | 0.280 | 0.760 | 0.61 |
Yp/s (g/g) | 0.083 | 0.083 | 0.086 | 0.090 | 0.162 |
Yp/x (g/g) | 0.332 | 0.320 | 0.330 | 0.280 | 0.46 |