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Fig. 5 | BMC Biotechnology

Fig. 5

From: Primary allogeneic mitochondrial mix (PAMM) transfer/transplant by MitoCeption to address damage in PBMCs caused by ultraviolet radiation

Fig. 5

Estimation of the RB (ROS production) of UVR-exposed PBMCs (monocytes and lymphocytes) and assessment of PBMC rescue by PAMM MitoCeption. a, b, c, d ROS production measured with DHR-PMA treatment and flow cytometry (n = 6, 6 PBMC donors exposed to UVR and PAMM of 3 donors) a. Monocytes behavior 1 h after 3 min exposure to UVR and rescue by PAMM MitoCeption. b. Monocytes behavior after 18 h culture and rescue by PAMM MitoCeption. c. Lymphocytes behavior 1 h after 3 min exposure to UVR and rescue by PAMM MitoCeption. d. Lymphocytes behavior after 18 h culture and rescue by PAMM MitoCeption. Analysis: the sample/control-average transformation was used, Anderson-Darling normality test was applied. Un-paired, ANOVA test and Student’s t-test are shown in the figure with an alpha-value of 0.05 (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001) to observe statistically significant differences

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