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Fig. 6 | BMC Biotechnology

Fig. 6

From: Novel anti-CD38 humanized mAb SG003 possessed enhanced cytotoxicity in lymphoma than Daratumumab via antibody-dependent cell-mediated cytotoxicity

Fig. 6

ADCC function of SG003 was stronger than Daratumumab. The EC50 value of SG003 was 0.0146 μg/mL in Raji (a), and 0.00056 μg/mL in Daudi cells (b), while in Daratumumab treated samples, the EC50 value was 0.0262 μg/mL and 0.0033 μg/mL, respectively. The unique epitope of SG003 might be beneficial to its stronger ADCC function

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BMC Biotechnology

ISSN: 1472-6750

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