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Fig. 2 | BMC Biotechnology

Fig. 2

From: Novel anti-CD38 humanized mAb SG003 possessed enhanced cytotoxicity in lymphoma than Daratumumab via antibody-dependent cell-mediated cytotoxicity

Fig. 2

Identification of humanized anti-CD38 antibodies to bind the antigen. a ELISA analysis of the three antibodies to bind the coated CD38. Both CDR-grafted 3G3 (anti-CD38-CDR) and the SDR-grafted 3G3 (anti-CD38-SDR) showed similar antigen binding activity to 3G3 (anti-CD38) on a dose-dependent manner; b BiAcore analysis of the three antibodies to bind soluble CD38, showing that the SDR-grafted 3G3 possessed similar affinity to 3G3

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BMC Biotechnology

ISSN: 1472-6750

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