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Table 1 Summary of off-targeting results for Ig Heavy chain. Five pigs were tested for each potential off-target gene. Five additional pigs were tested for the AR and RBFOX1 gene. Eight potential off target events were found in the AR gene and seven potential off-target events were found in the RBFOX1 gene. No off-target events were found in the other potential off-target genes

From: Frequency of off-targeting in genome edited pigs produced via direct injection of the CRISPR/Cas9 system into developing embryos

Ig Heavy chain

Gene

Number of pigs

Number of off-target events (%)

5′ to LRRF1P1

5

0 (0%)

EDIL3

5

0 (0%)

AR

10

8 (80%)

MYLK3

5

0 (0%)

RBFOX1

10

7 (70%)

CCDC60

5

0 (0%)