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Table 3 IC50 of each parent, mutant derivative, and complementation derivative strain and the percent differences of tolerance relative to the parent strain

From: Characterizing active transportation mechanisms for free fatty acids and antibiotics in Synechocystis sp. PCC 6803

Treatment   SD100 SD100 Δslr2131 SD100 Δslr2131 pacrB SD100 Δsll0180 SD100 Δsll0180 pSacrA
Amp IC50 955.2 ± 256 μg/mL 1280 ± 230 μg/mL (ns) 891 ± 117 μg/mL (ns) 598 ± 296 μg/mL 577.0 ± 23.2 μg/mL
% diff from SD100 0% 34% −6.7% 37% 39%
Cm IC50 2.290 ± 0.401 μg/mL 0.586 ± 0.142 μg/mL 2.124 ± 1.004 μg/mL (ns) 1.442 ± 0.206 μg/mL 4.73 ± 1.47 μg/mL
% diff from SD100 0% −74% −7.2% −37% 106%
Ery IC50 0.358 ± 0.081 μg/mL 0.054 ± 0.002 μg/mL 0.103 ± 0.019 μg/mL 0.172 ± 0.1 μg/mL 0.144 ± .028 μg/mL
% diff from SD100 0% −85% −71% −52% −60%
Treatment   SD277 SD277 Δslr2131 SD277 Δslr2131 pacrB SD277 Δsll0180 SD277 Δsll0180 pSacrA
Amp IC50 1570 ± 170 μg/mL 1001 ± 120 μg/mL 980.3 ± 37 μg/mL 450 ± 119 μg/mL 286.6 ± 113.8 μg/mL
% diff from SD277 0% −36% −38% −71% −82%
Cm IC50 4.749 ± 1.043 μg/mL 1.873 ± 0.354 μg/mL 3.305 ± 1.100 μg/mL (ns) 1.085 ± 0.589 μg/mL 3.486 ± 1.027 μg/mL (ns)
% diff from SD277 0% −61% −30% −77% −27%
Ery IC50 0.427 ± 0.249 μg/mL 0.171 ± 0.044 μg/mL 0.095 ± 0.007 μg/mL 0.034 ± 0.007 μg/mL 0.075 ± 0.014 μg/mL
% diff from SD277 0% −60% −78% −92% −82%
  1. The basis for the comparison in this table were the parent strains, either SD100 or SD277, featured in the third column. The data values for each derivative strain are significantly different from the parent strain unless otherwise noted with “(ns)”