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Table 7 Kinetic Parameters for A. niger cell growth and pectinase production under different cultivation conditions

From: Bioprocess optimization for pectinase production using Aspergillus niger in a submerged cultivation system

Parameters Shake Flask Bioreactor
Un-optimized Medium Optimized Medium Batch Fed-batch
Controlled pH Uncontrolled pH
Xmax (g/L) 2.26 2.29 3.28 2.38 6.58
μ (h−1) 0.01 0.01 0.01 0.01 n.d.
Pecmax (U/mL) 27.2 (60 h) 76.35 (36 h) 109.63 (84 h) 99.55 (84 h) 450 (108 h)
QPec (U/mL/h) 0.57 2.12 0.86 0.94 7.33
YPec/X (U/g) 12,517 (48 h) 38,270 (36 h) 46,283 (42 h) 43,760 (84 h) 75,762 (94 h)
  1. n.d. Not determined
  2. Xmax: maximal cell dry weight, μ: specific growth rate; Pecmax: maximal pectinase production; QPec: pectinase production rate; YPec/X: yield of pectinase on biomass