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Fig. 5 | BMC Biotechnology

Fig. 5

From: Development of a vitrification method for preserving human myoblast cell sheets for myocardial regeneration therapy

Fig. 5

Effect of vitrification on the in vivo cardiac function of transplanted cell sheets. a Protocol for the analysis of cardiac function using an MI nude rat model. b Evaluation of EF before transplantation and at 2 and 4 weeks (W) after transplantation. Results are expressed as the means ± SD at each time point; *p < 0.05. c Evaluation of FS before transplantation and at 2 and 4 weeks after transplantation. Results are expressed as the means ± SD at each point; *p < 0.05. d Evaluation of the ΔLVDd before transplantation and at 4 weeks after transplantation. Results are expressed as the means ± SD; *p < 0.05. e Evaluation of the ΔLVDs before transplantation and at 4 weeks after transplantation. Results are expressed as the means ± SD; *p < 0.05. f Evaluation of the ΔIVSd before transplantation and at 4 weeks after transplantation. These results were evaluated in the 3 treatment groups: the fresh (cell sheets used without further treatment; n = 11), vitrification (n = 11), and sham operation groups (n = 10). Results are expressed as the means ± SD; *p < 0.05

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BMC Biotechnology

ISSN: 1472-6750

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