Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice

Table 4 Immunization strategy via oral administration in mice

Group	Mouse Strain	Immunized with:	Dose	Route	No of mice
1	Balb/c	PBS	100 μl	Oral	7
2	Balb/c	L. plantarum (Lp)	100 μl of 1 × 10⁹ cfu/ml	Oral	7
3	Balb/c	Lp ACERL	50 μg antigen + 100 μl of 1 × 10⁹ cfu/ml	Oral	7
4	Balb/c	Lp ACERL + mIL-12	50 μg antigen + 50 μl of 1 × 10⁹ cfu/ml + 50 μl of 1 × 10⁹ cfu/ml	Oral	7
5	Balb/c	mIL-12	100 μl of 1 × 10⁹ cfu/ml	Oral	7
6	Balb/c	ACERL	50 μg antigen	Oral	7

ISSN: 1472-6750