Fig. 4From: Comparison of solvate ionic liquids and DMSO as an in vivo delivery and storage media for small molecular therapeuticsSU5402 exposure in developing zebrafish embryos. Embryos are exposed to SU5402 (d) at 2.5 μM (b & c) or 5 μM (e & f) in either DMSO or G4TFSA display the reported characteristics of FGF signaling inhibition compared to control (untreated (a) or DMSO exposed only (b & e)): lack of pectoral fin induction (marked by an asterisk), malformation of the otic vesicle (arrow). Lloss of MHB (open arrow head) was observed in embryos treated with 5 μM DEAB. 100× magnificationBack to article page