Table 1 Table of proteins showing the highest increase in abundance in young (n = 7) and old (n = 6) tenocyte-derived constructs, according to fold change
From: Donor age affects proteome composition of tenocyte-derived engineered tendon
Highest mean condition | Accession (human) | Protein description | Function | Peptide count | Fold change | ANOVA (p value) |
|---|---|---|---|---|---|---|
TEC derived from old cells | O94875 | Sorbin and SH3 domain containing protein 2 | Actin filament organization | 10 | 5,1 | 0,02 |
V9HWA5 | Calponin 1 | Actin binding, calmodulin binding | 4 | 3,6 | 0,02 | |
P02461 | Collagen type III alpha 1 | ECM Collagen | 38 | 3,5 | 0,01 | |
O43294 | Transforming growth factor beta induced protein | ECM Glycoprotein | 3 | 3,2 | 0,04 | |
Q05707 | Collagen type XIV alpha 1 | ECM Collagen | 3 | 3,0 | 0,02 | |
P08123 | Collagen type I alpha 2 | ECM Collagen | 48 | 3,0 | 0,00 | |
Q8WX93 | Palladin, cytoskeletal associated protein | Enzyme | 20 | 3,0 | 0,02 | |
TEC derived from young cells | Q99623 | Prohibitin 2 | Transcription regulator | 2 | 3,9 | 0,05 |
P05106 | Integrin beta 3 | Transmembrane receptor | 2 | 2,8 | 0,01 | |
P11166 | Solute carrier family 2 member 1 | Transporter | 3 | 2,2 | 0,02 | |
P07919 | Cytochrome b-c1 complex subunit 6 | Enzyme | 2 | 2,1 | 0,05 | |
P07093 | Serpin family E member 2 | ECM Regulator | 3 | 2,1 | 0,04 | |
P08648 | Integrin alpha 5 | Transmembrane receptor | 2 | 2,1 | 0,02 | |
| Â | P30049 | ATP synthase subunit delta, mitochondrial | Enzyme | 5 | 2,0 | 0,04 |