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Table 1 Table of proteins showing the highest increase in abundance in young (n = 7) and old (n = 6) tenocyte-derived constructs, according to fold change

From: Donor age affects proteome composition of tenocyte-derived engineered tendon

Highest mean condition Accession (human) Protein description Function Peptide count Fold change ANOVA (p value)
TEC derived from old cells O94875 Sorbin and SH3 domain containing protein 2 Actin filament organization 10 5,1 0,02
V9HWA5 Calponin 1 Actin binding, calmodulin binding 4 3,6 0,02
P02461 Collagen type III alpha 1 ECM Collagen 38 3,5 0,01
O43294 Transforming growth factor beta induced protein ECM Glycoprotein 3 3,2 0,04
Q05707 Collagen type XIV alpha 1 ECM Collagen 3 3,0 0,02
P08123 Collagen type I alpha 2 ECM Collagen 48 3,0 0,00
Q8WX93 Palladin, cytoskeletal associated protein Enzyme 20 3,0 0,02
TEC derived from young cells Q99623 Prohibitin 2 Transcription regulator 2 3,9 0,05
P05106 Integrin beta 3 Transmembrane receptor 2 2,8 0,01
P11166 Solute carrier family 2 member 1 Transporter 3 2,2 0,02
P07919 Cytochrome b-c1 complex subunit 6 Enzyme 2 2,1 0,05
P07093 Serpin family E member 2 ECM Regulator 3 2,1 0,04
P08648 Integrin alpha 5 Transmembrane receptor 2 2,1 0,02
  P30049 ATP synthase subunit delta, mitochondrial Enzyme 5 2,0 0,04
  1. Only proteins with ≥2 unique peptides and p < 0.05 were presented. Abundant proteins in each group are also highlighted in Additional file 1