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Fig. 3 | BMC Biotechnology

Fig. 3

From: A fast and effective determination of the biodistribution and subcellular localization of fluorescent immunoliposomes in freshly excised animal organs

Fig. 3

Representative intensity scaled NIRF images of mice organs showing distribution of liposomal fluorescence at different time points post injection. At 1 h post injection first pass distribution in lungs, kidneys, liver, gall bladder and preliminary release to the duodenum are seen for both FAP-IL and mEnd-IL. At 6 h post injection, FAP-IL is washed out from the lungs and partially from the liver and secreted to the gall bladder, but retained in the kidneys. Release from the gall bladder to the duodenum and excretion via the GIT is evident in the fluorescence movement from duodenum to the jejunum, ileum and colorectum with time. The mEnd-IL is retained in the lungs, kidneys and liver and only gradually eliminated via the GIT with time

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BMC Biotechnology

ISSN: 1472-6750

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