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Fig. 5 | BMC Biotechnology

Fig. 5

From: Virus-like particles derived from Pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain III-directed antibodies

Fig. 5

Determination of virus neutralization potency of antibodies induced by DENV-1 E VLPs. Immune sera were serially diluted two-fold and pre-incubated separately with DENV-1 (red curve), DENV-2 (green curve), DENV-3 (blue curve) and DENV-4 (black curve). The antibody-virus complexes were allowed to infect Vero cells and neutralizing antibody titers (FNT50) were determined by using FACS analysis. The Y and X axes of the graph represent % infected cells and log of reciprocal of sera dilution, respectively. The dotted horizontal line in the graph represents 50 % infection. The table on top of the panel lists the FNT50 titers of DENV-1 E antiserum against all the four serotypes

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BMC Biotechnology

ISSN: 1472-6750

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