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Fig. 1 | BMC Biotechnology

Fig. 1

From: Enhancement of D-lactic acid production from a mixed glucose and xylose substrate by the Escherichia coli strain JH15 devoid of the glucose effect

Fig. 1

Engineering an E. coli strain devoid of the glucose effect for D-lactic acid production from a mixture of glucose and xylose. Genes encoding important enzymes are indicated by italics. The relevant genes/enzymes are: ldhL, L-lactate dehydrogenase; ldhA, D-lactate dehydrogenase; adhE, alcohol dehydrogenase; ackA, acetate kinase; pflB, pyruvate formate lyase; frdABCD, fumarate reductase; glk, glucokinase; xylA, xylose isomerase; xylB, xylulokinase; xylFGH, xylose ABC transporter; xylE, xylose/proton symporter; ptsG, subunit of glucose PTS permease; EI-Hpr-IIA, phosphoenolpyruvate-protein phosphotransferase system; AC-P, adenylate cyclase; ~P, high-energy phosphate from a phosphorylated compound; Crp, cAMP receptor protein; Crp-cAMP, transcriptional dual regulator; GalP, galactose transporter; Mgl, galactose transporter. Symbols: the stop and delta (∆) signs indicated the relevant genes (adhE, frdBC, ackA, pflB, ptsG, ldhL) were deleted

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BMC Biotechnology

ISSN: 1472-6750

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