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Fig. 10 | BMC Biotechnology

Fig. 10

From: Hydrodynamic loading in concomitance with exogenous cytokine stimulation modulates differentiation of bovine mesenchymal stem cells towards osteochondral lineages

Fig. 10

TGF-β3 supplementation of 10 ng/mL is the most ubiquitous supplementation protocol for chondrogenic cultures found in the literature. When hydrodynamic loading is introduced in concert at these levels of exogenous supplementation, SOX9 and COL2A1 are modulated in high shear environments. Osteogenic markers remain at levels comparable to static controls. Genes with statistically significant regulation are highlighted with a red box. Statistically significance is indicated by asterisks

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BMC Biotechnology

ISSN: 1472-6750

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