Table 1 Summary of the different epigenetic results and correlation to recombinant mRNA expression in the PT1-CHO cell lines
Cell lines | mRNA HC/LC (%) | ChIP enrichment (% Input) | FAIRE | M.SssI map (% nucleosome occupancy) | % Methylation | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
H2A | H3.3 | H2A.Z | H3K9ac | H3K9me3 | H3K4me3 | H3K27me3 | Nuc 853 | Nuc 1008 | Â | |||
PT1-1 | 1.00 | 19.50 | 22.00 | 5.26 | 2.17 | 3.90 | 8.04 | 17.20 | 46.90 | 60.00 | 86.67 | 6.25 |
PT1-7 | 53.50 | 6.67 | 79.94 | 135.97 | 218.15 | 66.96 | 5.41 | 32.23 | 2.60 | 60.67 | 66.67 | 0.00 |
PT1-30 | 22.36 | 13.31 | 16.73 | 11.13 | 61.99 | 97.82 | 17.90 | 51.18 | 6.00 | 73.33 | 80.00 | 2.08 |
PT1-55 | 104.00 | 2.93 | 66.45 | 7.29 | 189.00 | 577.78 | 16.40 | 47.40 | 207.50 | 87.50 | 62.50 | 0.71 |
Pearson correlation |  | −0.96 | 0.76 | 0.12 | 0.83 | 0.91 | 0.30 | 0.54 | 0.77 | 0.76 | −0.95 | −0.75 |