Single point mutation in adeno-associated viral vectors -DJ capsid leads to improvement for gene delivery in vivo

BMC Biotechnology

Table 4 The average titers of AAV-DJ and its three single point mutant vectors for packaging double-strand and single-strand reporter genes

Vector	Double-strand GFP reporter	Single-strand luciferase reporter
AAV-DJ	1.08x10¹⁰vg/ml	6.44x10¹⁰vg/ml
K137R	4.94x10¹⁰vg/ml	1.84x10¹¹vg/ml
T251A	1.56x10¹⁰vg/ml	9.95x10¹⁰vg/ml
S503A	1.44x10¹⁰vg/ml	8.47x10¹⁰vg/ml

ISSN: 1472-6750