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Fig. 3 | BMC Biotechnology

Fig. 3

From: Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clones

Fig. 3

Box plot of the relative gene expression ratios for the stable (S) and unstable (US) clones. The relative gene expression ratios for Fgfr2, BX842664.2/Hist1h3c, AC115880.11, hDhfr, Hist1h2bc, Mmp10, CU459186.17, E130203b14, Cspg4, C1qtnq, Foxp2, Egr1 and Ptpre (log 2 FC) for the stable (S) and unstable (UN) clones are shown. The relative expression values were normalised using the geometric mean of the reference genes Actb/Gapdh. The threshold for statistical significance between the relative expression ratios of the stable and unstable clones was set to P = 0.05 (Welch two tailed t-tests). Box plots for genes where such differences were observed are represented in dark grey, in contrast to the white boxplots for non-significant genes

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