Fig. 3From: Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clonesBox plot of the relative gene expression ratios for the stable (S) and unstable (US) clones. The relative gene expression ratios for Fgfr2, BX842664.2/Hist1h3c, AC115880.11, hDhfr, Hist1h2bc, Mmp10, CU459186.17, E130203b14, Cspg4, C1qtnq, Foxp2, Egr1 and Ptpre (log 2 FC) for the stable (S) and unstable (UN) clones are shown. The relative expression values were normalised using the geometric mean of the reference genes Actb/Gapdh. The threshold for statistical significance between the relative expression ratios of the stable and unstable clones was set to P = 0.05 (Welch two tailed t-tests). Box plots for genes where such differences were observed are represented in dark grey, in contrast to the white boxplots for non-significant genesBack to article page