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Figure 1 | BMC Biotechnology

Figure 1

From: PHDs inhibitor DMOG promotes the vascularization process in the AV loop by HIF-1a up-regulation and the preliminary discussion on its kinetics in rat

Figure 1

The Hydroxylase pathway of HIF-1α and DMOG structure. The Prolyl hydroxylase (PHD) is catalyzed with the presence of oxygen and Fe (II), then subsequently involved in the HIF protein degradation. Otherwise, HIF-1α is stabilized and dimerized with the HIF-β, and activates the target genes. DMOG structure (From SciFinder®).

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BMC Biotechnology

ISSN: 1472-6750

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