Modifications of cysteine residues in the transmembrane and cytoplasmic domains of a recombinant hemagglutinin protein prevent cross-linked multimer formation and potency loss

Table 5 HAI titers for wild-type and Cys SDV H3 rHAs

H3 HA protein	HAI titer
H3 HA protein	Rabbit poly clonal anti-H3 rHA Ab	Sheep polyclonal anti-H3 HA Ab
Wild-type	10240	2560
2Cys	5120	2560
3Cys	5120	1280
5Cys	10240	2560
#70 H3 HA CBER	5120	2560

ISSN: 1472-6750