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Figure 11 | BMC Biotechnology

Figure 11

From: Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function

Figure 11

Chloroplast synthesized human IGF-1 stimulates the growth and proliferation of human cells in culture. Proliferation of human megakaryoblastic HU-3 cells were investigated by phase contrast light microscopy at 4 and 7 days after the addition of huIGF-1. Left panel: Four day HU-3 cell culture to which no chloroplast synthesized IGF-1 was added (400 × magnification). Right panel: HU-3 cell culture of the same age to which 62 ng/ml chloroplast-derived, partially purified IGF-1 was added at time zero (100 × magnification).

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BMC Biotechnology

ISSN: 1472-6750

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