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Table 1 Yields of recombinant proteins obtained in Nicotiana spp. using the TMV expression system.

From: Expression of HIV-1 antigens in plants as potential subunit vaccines

Recombinant protein (non-targeted)

TMV Expression (μg p24/kg)

Full length Pr55Gag

 

wtgag

<0.01

ngag

0.46 – 2.0

p 24

 

wtp24

172 – 13900

np24

230 – 17350

hp24

167 – 1000

  1. Levels of protein are expressed as μg p24 per kg of fresh leaf weight.
  2. wt = wildtype codon usage; n = Nicotiana spp. codon-optimised; h = human codon-optimised